Results 171 to 180 of about 290,820 (278)

Erratum: Energy budget and core-envelope motion in common envelope evolution

Monthly Notices of the Royal Astronomical Society, 2021
Luke Chamandy, Yisheng Tu, Eric G Blackman, Jonathan Carroll-Nellenback, Adam Frank, Baowei Liu, Jason Nordhaus   +6 more
openaire   +1 more source

Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells

Advanced Science, EarlyView.
Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale, Luca Messina, Valeria Panzetta, Stefania Saporito, Costantino Menna, Maurizio Ventre, Paolo A. Netti   +6 more
wiley   +1 more source

Antioxidation is a Common Defense Strategy for Different Species Under Mechanical Stress. [PDF]

Adv Genet (Hoboken)
Zhu F, Huang K.
europepmc   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

Advanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin, Giada Vanni, Veronica Torresan, Margherita Pelosin, Rebecca Busetto, Anna Citron, Ambela Suli, Paolo Contessotto, Carlo Albanese, Francesca Zanconato, Tito Panciera, Stefano Piccolo, Giovanna Brusatin   +12 more
wiley   +1 more source

Genome characterization of the SARS-CoV-2 omicron in Cameroon. [PDF]

BMC Infect Dis
Monamele CG, Essengue LLM, Moumbeket-Yifomnjou MH, Ilouga PV, Mounchili-Njifon A, Touoyem IP, Longla EM, Njankouo RM, Modiyinji AF, Omah IF, Njouom R.   +10 more
europepmc   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

The impact of variations in the chikungunya genome on the clinical manifestations and transmission of the disease. [PDF]

J Family Med Prim Care
Rawat SK, Singh AK, Kale D, Sikenis M, Prajapati B, Nema S, Biswas D, Christina AE, Nema RK.   +8 more
europepmc   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

Advanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun, Peng‐Yi Huang, Zhi‐Ruo Zhang, Cong‐Fen Gao, Subba Reddy Palli, Shun‐Fan Wu   +5 more
wiley   +1 more source

A young progenitor for the most common planetary systems in the Galaxy. [PDF]

Nature
Livingston JH, Petigura EA, David TJ, Masuda K, Owen J, Nesvorný D, Batygin K, de Leon J, Mori M, Ikuta K, Fukui A, Watanabe N, Orell Miquel J, Murgas F, Parviainen H, Korth J, Libotte F, Abreu García N, Gallardo PPM, Narita N, Pallé E, Tamura M, Yonehara A, Ridden-Harper A, Bieryla A, Trani AA, Mamajek EE, Ciardi DR, Gorjian V, Hillenbrand LA, Rebull LM, Newton ER, Mann AW, Vanderburg A, Stefánsson G, Mahadevan S, Cañas C, Ninan J, Higuera J, Todorov K, Désert JM, Pino L.   +41 more
europepmc   +1 more source

VE‐Cadherin–Actin Regulation Promotes Mechanotransduction and Monolayer Maturation Involving a Tension‐Sensitive Intermediate State

Advanced Science, EarlyView.
This study investigates how endothelial monolayers balance cohesion and plasticity during mechanical stimulation. In HUVECs, shear stress induces a tension‐sensitive intermediate state in which junctional VE‐cadherin and actomyosin relaxation levels coordinate actin/integrin remodeling. This rapid, reversible state strengthens cell junctions, preserves
Jonas Franz, Maria Odenthal‐Schnittler, Jan Philip Kipcke, Jochen Seebach, Zahra Labbaf, Franziska Merten, Vesna Bojovic, Muna Taha, Johannes A. Eble, Erez Raz, Milos Galic, Hans Schnittler   +11 more
wiley   +1 more source