Results 241 to 250 of about 290,820 (278)

V3101 Cyg: A Cataclysmic Variable Born with a Brown Dwarf Donor

Ramirez S, Gänsicke B, Sahu S, Belloni D, Pala A, Koester D, Toloza O, Lagos-Vilches F.   +7 more
europepmc   +1 more source

Evolution of antiviral resistance captures a transient interdomain functional interaction between chikungunya virus envelope glycoproteins. [PDF]

mBio
Battini L, Thannickal SA, Tejerina Cibello M, Bollini M, Stapleford KA, Álvarez DE.   +5 more
europepmc   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source

The Dynamics of the ESCRT Machinery in Open Mitosis from Physiology to Pathology. [PDF]

Cells
La Torre M, Cannistrà F, Burla R, Saggio I.   +3 more
europepmc   +1 more source

Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform

Advanced Science, EarlyView.
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng, Jiahao Lin, Qiushuang Zhang, Xiangdong Zhang, Yicong Dai, Jinghong Li   +5 more
wiley   +1 more source

Reprogramming innate immunity through viral interference: A double-edged strategy for enhancing and containing gene therapies. [PDF]

Mol Ther Nucleic Acids
Liu Z, Song S.
europepmc   +1 more source

Sensing and Filtering Environmental Fluctuations: The Case of Biomolecular Condensates in Plants

Advanced Science, EarlyView.
The diversity of plant condensates reflects constraints of sessile organisms to coordinate postembryonic development with environmental adaptation. This review examines how plants employ condensates to integrate temperature, light, redox, and nutrient signals.
Panagiotis N. Moschou, Dorothee Staiger
wiley   +1 more source

Descriptive transcriptomic profiling differentiates oral leukoplakia from proliferative verrucous leukoplakia and reveals distinct molecular signatures. [PDF]

Med Oral Patol Oral Cir Bucal
Pérez-Sayáns M, Vieira-E-Silva FF, Fernández-Rozadilla C, Carracedo Á, Carlés-González S, Lorenzo-Pouso AI, Pérez-Jardón A, Gándara-Vila P, García-García A, Suárez-Peñaranda JM, Blanco-Carrión A, Chamorro-Petronacci CM.   +11 more
europepmc   +1 more source

Electrically Tunable Room‐Temperature Microwave Oscillations in GaN/AlN Triple‐Barrier Resonant Tunneling Diodes

Advanced Electronic Materials, EarlyView.
III‐nitride semiconductors have revolutionized optoelectronics, enabling transformative technologies such as high‐efficiency LEDs and lasers. However, their use in intersubband optoelectronics has remained limited. This work marks an important step forward by demonstrating highly coherent inter‐well resonant tunneling injection in III‐nitride ...
Jimy Encomendero, Naomi Pieczulewski, Eegene Chung, Vladimir Protasenko, David A. Muller, Debdeep Jena, Huili Grace Xing   +6 more
wiley   +1 more source

A narrative review of SARS-CoV-2 variants and long COVID. [PDF]

J Thorac Dis
Chai X, Qi H, Liu X, Zhou F, Jiang Y, Wu M, Lian S, Wang L, Bao Y.   +8 more
europepmc   +1 more source