Results 141 to 150 of about 9,432 (264)

Establishing Sensory Neurons as Therapeutic Targets in Peripheral Neuropathy Driven by Polyglutamine Expanded Murine ATXN3

Annals of Neurology, EarlyView.
Repeat expansion disorders frequently involve peripheral neuropathy, yet mechanisms remain unclear. Using a spinocerebellar ataxia type 3 (SCA3) Knock‐In Atxn3Q300/Q6, we identify progressive sensorimotor deficits, peripheral nerve pathology, and dorsal root ganglia RNA splicing dysregulation.
Juan P. Mato, John M. Hayes, Jacen Emerson, Maeha Sridharan, Toluwani Adelaja, Arsal Naeem, Alexandra F. Putka, Hayley S. McLoughlin   +7 more
wiley   +1 more source

Pearl's causality for integrating ecological datasets: A case study on Myricaria germanica in northern Italy

Applications in Plant Sciences, EarlyView.
Abstract Premise Applied ecology can significantly influence policy decisions on environmental issues. Therefore, research in this field should be as transparent and reproducible as possible. Existing expertise from a broad range of disciplines should also be integrated into ecological research to allow researchers to maximize understanding of complex ...
Kailin Weitkämper, Kilian Rückschloß, Tommaso Sitzia, Bruno Michielon, Silke Werth, Felix Weitkämper   +5 more
wiley   +1 more source

Balancing the blue economy and multiple stressor management in marine spatial planning at the land-sea interface. [PDF]

NPJ Ocean Sustain
Wilson R, Reiter S, Santos CF, Agardy T, Wedding LM.   +4 more
europepmc   +1 more source

Oldest well‐preserved euprimate petrosal, from the early Eocene of India (Vastan Lignite Mine, Gujarat)

The Anatomical Record, EarlyView.
Abstract An exquisitely preserved, isolated partial petrosal with associated fragmentary stapes is described from the Vastan Lignite Mine (Gujarat, India), dated to the early Eocene (~54.5 Ma). Several anatomical traits (e.g., large petrosal plate; posterolateral entry of the internal carotid artery to the tympanic cavity; bony tubes surrounding the ...
Mary T. Silcox, Kenneth D. Rose, Rachel H. Dunn, Kishor Kumar, Rajendra S. Rana, Ashok Sahni, Lachham Singh, Thierry Smith, Jordan W. Crowell   +8 more
wiley   +1 more source

Unlocking the potential of other effective area-based conservation measures (OECMs) for achieving conservation targets: A global scoping review. [PDF]

Ambio
Petza D, Amorim E, Lamine EB, Colloca F, Dominguez Crisóstomo E, Fabbrizzi E, Fraschetti S, Galparsoro I, Giakoumi S, Kruse M, Stelzenmüller V, Katsanevakis S.   +11 more
europepmc   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Demystifying invasivorism as a management strategy. [PDF]

Proc Natl Acad Sci U S A
Oficialdegui FJ, Bedmar S, Kouba A, Vimercati G, Roessink I, Clavero M.   +5 more
europepmc   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Fishery nutrient profiles provide practical guidance for nutrition-sensitive small-scale fisheries management in Timor-Leste. [PDF]

Nat Food
Longobardi L, Bonis-Profumo G, Altarturi H, Bogard J, Dos Reis Lopes J, Kolding J, Sozinho V, Tilley A.   +7 more
europepmc   +1 more source

Multi‐Omic Profiling Reveals Immune Cell Priming Signature Linked to Lupus Prognosis

Arthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) is a multiorgan disease with widespread immune dysregulation and significant unmet clinical need. Blood‐based gene expression studies have advanced our understanding of SLE pathogenesis but may overlook critical tissue‐specific mechanisms that drive disease heterogeneity and progression.
Michael A. Smith, Dominic Sinibaldi, Saifur Rahman, Chia‐Chien Chiang, Anna M. Hansen, Jill Henault, Carlos P. Roca, Shu Wang, Kamelia Zerrouki, Rebecca Filippi, Christopher Groves, Zerai Manna, Jun Chu, Michael Davis, Sarthak Gupta, Christopher Morehouse, Melissa de los Reyes, Rachel Ettinger, Roland Kolbeck, Mariana J. Kaplan, Miguel A. Sanjuan, Richard M. Siegel, Sarfaraz A. Hasni, Kerry A. Casey   +23 more
wiley   +1 more source