Results 171 to 180 of about 9,432 (264)

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

open access: yesBiotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady   +6 more
wiley   +1 more source

Glycoengineered Recombinant Alpha1‐Antitrypsin Results in Comparable In Vitro and In Vivo Activities to Human Plasma‐Derived Protein

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Alpha‐1‐antitrypsin (A1AT) is a multifunctional, clinically important, high‐value therapeutic glycoprotein that can be used for the treatment of many diseases, such as A1AT deficiency, diabetes, graft‐versus‐host disease, cystic fibrosis, and various viral infections. Currently, the only U.S. food and drug administration‐approved treatment for
Frances Rocamora   +12 more
wiley   +1 more source

Spatio‐Temporal Assessment of Fish Biodiversity in High‐Density Cascade Dam Rivers Using Environmental DNA Metabarcoding

open access: yesBiological Diversity, EarlyView.
This study employed eDNA technology for biodiversity surveys and conducted high‐density spatiotemporal eDNA sampling to evaluate ecosystem‐scale patterns across temporal, spatial, and habitat dimensions. We identified 97 fish species from 12 orders, 29 families, and 71 genera using eDNA technology. Spatially, fish diversity indices were correlated with
Changping Jiang   +5 more
wiley   +1 more source

The evidence base for ranger patrol effectiveness in conservation and how to improve it

open access: yesBiological Reviews, EarlyView.
ABSTRACT Ranger patrols are a cornerstone of wildlife protection efforts around the world and occur across all ecological governance systems. Evidence that patrols reduce threats to wildlife and enable their recovery has not been systematically examined previously.
Trina Rytwinski   +19 more
wiley   +1 more source

Two hundred years of historical spawning and nursery data for coregonine fishes in the Laurentian Great Lakes. [PDF]

open access: yesSci Data
Brant CO   +15 more
europepmc   +1 more source

Dynamics of biotic resistance to plant invasions

open access: yesBiological Reviews, EarlyView.
ABSTRACT Biotic resistance, the reduction in invasion success caused by native communities, plays an important role in the long‐term dynamics of biological invasions. A large body of empirical research on biotic resistance has accumulated since the last comprehensive review on the subject 20 years ago, enabling us to achieve a refined understanding of ...
Christine S. Sheppard   +13 more
wiley   +1 more source

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