Results 231 to 240 of about 3,960,125 (345)

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Direct Carotid-Cavernous Fistula due to Aneurysmal Rupture with Residual Aortic Dissection Treated by Coil Embolization via Direct Puncture of the Common Carotid Artery: A Case Report. [PDF]

J Neuroendovasc Ther
Oichi Y, Nagata M, Okawa M, Morimoto T, Yoshimoto N, Takahashi Y, Taki J, Yamada K.   +7 more
europepmc   +1 more source

A COMMON FIXED POINT THEOREM IN NON-ARCHIMEDEAN MENGER PM-SPACES [PDF]

, 2009
Servet Kütükçü, Sushil Sharma
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Cognitive behavioral interventions for depression and anxiety in adults with neurological disorders: a systematic review and meta-analysis: reply to Zhou et al. [PDF]

Psychol Med
Gandy M, Woldhuis T, Wu W, Youssef M, Bisby MA, Dear BF, Heriseanu AI, Scott AJ.   +7 more
europepmc   +1 more source

Strict Contractive Conditions and Common Fixed Point Theorems in Cone Metric Spaces [PDF]

, 2009
Zoran Kadelburg, Stojan Radenović, Božidar Rosić   +2 more
openalex   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

The domestication of the wolf larynx-testing the neural crest connection. [PDF]

R Soc Open Sci
Hansen J, Grunstra NDS, Fitch WT, Kitchener AC, Gumpenberger M, Lesch R.   +5 more
europepmc   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

New fixed points of mixed monotone operators with applications to nonlinear integral equations. [PDF]

PLoS One
Xu S, Han Y, Lin S, Zhou G.
europepmc   +1 more source