The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
The set of common fixed points of an n-parameter continuous semigroup of mappings [PDF]
In this paper, using Kronecker's theorem, we discuss the set of common fixed points of an n-parameter continuous semigroup of mappings. We also discuss convergence theorems to a common fixed point of an n-parameter nonexpansive semigroup.
arxiv
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Common fixed points of commutative semigroups of nonexpansive mappings [PDF]
In this paper, we discuss characterizations of common fixed points of commutative semigroups of nonexpansive mappings. We next prove convergence theorems to a common fixed point. We finally discuss nonexpansive retractions onto the set of common fixed points. In our discussion, we may not assume the strict convexity of the Banach space.
arxiv
Common Fixed Point Theorems for Four Transformations in Vector S-metric Spaces [PDF]
We establish some common fixed point results for four transformations in vector S-metric spaces by using the notion of weakly compatibility (WC) and occasionally weakly compatibility (OWC). The first theorem is proved by using the concept of CLR (p,q) property (common limit range property w.r.t.
arxiv
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti+3 more
wiley +1 more source
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink+6 more
wiley +1 more source
New common fixed point theorems for multivalued maps
Common fixed point theorems for a new class of multivalued maps are obtained, which generalize and extend classical fixed point theorems of Nadler and Reich and some recent Suzuki type fixed point theorems.
S. L. Singh+3 more
doaj +1 more source
A New Shrinking projection Algorithm for an infinite family of Bregman weak relatively nonexpansive mappings in a Banach Space [PDF]
In this paper, using a new shrinking projection method and generalized resolvents of maximal monotone operators and generalized projections, we consider the strong convergence for finding a common point of the fixed points of a Bregman quasi-nonexpansive mapping, and common fixed points of a infinite family of Bregman weak relatively nonexpansive ...
arxiv
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi+3 more
wiley +1 more source