Results 121 to 130 of about 673,529 (296)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Common fixed points versus invariant approximation for noncommutative mappings

open access: yesJournal of Numerical Analysis and Approximation Theory, 2008
The aim of this paper is to obtain common fixed points as invariant approximation for noncommuting two pairs of mappings. As consequences, our works generalize the recent works of Nashine [9] by weakening commutativity hypothesis and by increasing the ...
Hemant Kumar Nashine
doaj   +2 more sources

Common Fixed Points of (α,η) − (θ,ϝ) Rational Contractions with Applications

open access: yesJournal of Mathematics, 2019
We present the notion of set valued (α,η)-(θ,ϝ) rational contraction mappings and then some common fixed point results of such mappings in the setting of metric spaces are established.
Mujahid Abbas   +2 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

On coincidence and common fixed points of nearly densifying mappings

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2000
Coincidence and common fixed point theorems for certain new classes of nearly densifying mappings are established. Our results extend, improve, and unify a lot of previously known theorems.
Zeqing Liu, Jeong Sheok Ume
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Common Fixed Points for Nonlinear Quasi-Contractions of SiriT Type

open access: yes, 2020
We establish common fixed points theorems for two self-mappings satisfying a nonlinear contractive condition ofĆirić type with a Q-function. Furthermore, using the scalarization method, we deduce some results of common fixed point in tvs-cone metric ...
Fei He
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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