Results 271 to 280 of about 2,884,547 (321)

Stroke Technology Diffusion in Rural Settings: Differential Exposure to Certification Levels by Community Income Levels. [PDF]

Neurology
Shen YC, Spencer M, Hsia RY.
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Rare nonunion of tibial plateau fracture with patellar tendon rupture: A case report. [PDF]

Medicine (Baltimore)
Xiong T, Fan ZF, Zeng W.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Immune Modulation in the Tumor Microenvironment: Bifurcation Analysis of Cancer-CTL-Monocyte Dynamics. [PDF]

Bull Math Biol
Hernandez-Lopez E, Milne R, Wang X.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Impact of Fixed-Dose Combination Versus Single-Component Therapy for Benign Prostatic Hyperplasia-Related Urinary Symptoms on Persistence, Adherence, and Satisfaction in a Real-Life Setting. [PDF]

Pharmaceuticals (Basel)
Małkowski M, Chudek A, Almgren-Rachtan A, Chudek JT, Chłosta PL.   +4 more
europepmc   +1 more source

Building envelope thermal performance testing dataset (Co-heating, QUB, ISO-9869 U-values) from a retrofitted heritage building (unoccupied dwelling). [PDF]

Data Brief
Giraldo-Soto C, Erkoreka A, Uriarte A, García-Gáfaro C.   +3 more
europepmc   +1 more source

Multiple amplitude wavelength modulation spectroscopy for concomitant measurement of pressure and concentration of methane. [PDF]

Sci Rep
Santini L, Coelho LCC, Floridia C.
europepmc   +1 more source

Environmental dynamics shape human learning: change points versus random walks

Foucault C, Weber LA, Hunt L.
europepmc   +1 more source