Results 91 to 100 of about 2,437,627 (308)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The common good

, 1999
editoria

core  

AI Literacy for the Common Good

Weizenbaum Journal of the Digital Society
Artificial Intelligence (AI) does not provide solutions to pressing social questions, such as those pertaining to a peaceful, sustainable, and socially acceptable world.
Stefan Ullrich, Reinhard Messerschmidt
doaj   +1 more source

Forging a Social Movement to Dismantle Entrenched Power and Liberate Primary Care as a Common Good. [PDF]

Ann Fam Med, 2023
Grumbach K.
europepmc   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

COVID-19 vaccine as a common good. [PDF]

J Glob Health, 2021
Borges GS, Dos Santos BF.
europepmc   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Fear trumps the common good: Psychological antecedents of vaccination attitudes and behaviour. [PDF]

Acta Psychol (Amst), 2022
Adamus M, Čavojová V, Mikušková EB.
europepmc   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

MONUMENTAL TREES AS COMMON GOOD: THE CENSUS AT THE BASE OF A GOOD LANDSCAPE PLANNING.

, 2014
The landscape transformation processes in Italy, in the last decades, involve mainly environments on the fringes of city. In the transformations of land use in urban areas, whose boundaries are not uniquely defined, the naturalistic landscapes take on ...
TOLLI, MICHELA, Fabio Recanatesi
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