Results 91 to 100 of about 10,765,825 (287)

CCG News Issue 5, December 6, 2021

open access: yes, 2021
Issue of CCG News, a publication of Peace and Justice Studies at the University of Scranton, in collaboration with Christians for the Common ...
University of Scranton. Christians for the Common Good
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Identité et perspectives d’un ordre public écologique

open access: yesDroit et Cultures, 2014
More than a terminological development, this article aims at analyzing the contents and the potentialities of a «tool» which allows to identify and to express essential social values connected to environmental protection.
Nadia Belaidi
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

The Inflation Reduction Act – implications for climate change, air pollution, and health

open access: yesThe Lancet Regional Health. Americas, 2023
Sanjay Rajagopalan, Philip J. Landrigan
doaj   +1 more source

Netwoks, Society and Common Good

open access: yesCultura Económica, 2019
Editorial
Carlos Hoevel
doaj  

AI Literacy for the Common Good

open access: yesWeizenbaum Journal of the Digital Society
Artificial Intelligence (AI) does not provide solutions to pressing social questions, such as those pertaining to a peaceful, sustainable, and socially acceptable world.
Stefan Ullrich, Reinhard Messerschmidt
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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