Results 111 to 120 of about 10,765,825 (287)

From patients to partners: evaluating a co-designed website for congenital hypogonadotropic hypogonadism

open access: yesEndocrine Connections
Background: Patients with congenital hypogonadotropic hypogonadism (CHH) are geographically dispersed and have unmet health and informational needs. Patients often rely on the Internet to learn about CHH, find expert care, and connect with other patients.
Andrew A Dwyer   +6 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Common Goods and the Common Good in John Duns Scotus

open access: yes
AbstractJohn Duns Scotus did not devote a treatise or even a question to the matter of the common good, or the good of the community, as opposed to the good of the individual. Throughout his moral and political writings, he did, however, provide a sketch of his views regarding the general nature of the common good, defined as what is to be preserved by
openaire   +1 more source

CCG News Issue 2, February 2, 2019

open access: yes, 2019
Issue of CCG News, a publication of Peace and Justice Studies at the University of Scranton, in collaboration with Christians for the Common ...
University of Scranton. Christians for the Common Good
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

On Education & the Common Good

open access: yesEducation Policy Analysis Archives, 1994
This response to Coulson's recent EPAA piece, "Human Life, Human Organizations, and Education," argues that Coulson is wrong about "human nature," social life, and the effects of unregulated capitalist markets.
John Covaleskie
doaj  

Home - About - Disclaimer - Privacy