Results 61 to 70 of about 8,169,081 (300)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Copyright as Opposed to Subversive of Common Good [PDF]

open access: yes, 2005
My article is on copyright. It tells how copyright which is an expression of idea is protected and the decline of the author/the rise of the work and consolidation in the copyright ...
Sambhar, Miss Aditi
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Utopia as Common Good

open access: yesGaudium Sciendi, 2017
The narrative that presents the "polis"of "Utopia"does not build an image of a "place without place", but demonstrates that which could and should be – at least structurally – the form of a real community, the one that erects itself as an act of "common-wealth/common-good/common-goodness".
openaire   +4 more sources

COVID-19 vaccine as a common good. [PDF]

open access: yesJ Glob Health, 2021
Borges GS, Dos Santos BF.
europepmc   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

COVID and the Common Good. [PDF]

open access: yesPhilos Manag, 2021
Latemore G.
europepmc   +1 more source

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