Results 101 to 110 of about 99,860 (311)

The relevance of the common goods approach to examine social enterprise - Insights from Ostrom to the SE field

, 2014
The relevance of the common goods approach to examine social enterprise - Insights from Ostrom to the SE ...
Le Polain, Maïté, Nyssens, Marthe, The Fourth IAP-Day - From common goods to social banking: sharing theories and field analyses, Perilleux, Anaïs   +3 more
core  

Contributing or Free-Riding? Voluntary Participation in a Public Good Economy [PDF]

We consider a (pure) public goods provision problem with voluntary participation in a quasi-linear economy. We propose a new hybrid solution concept, the free-riding-proof core (FRP-Core), which endogenously determines a contribution group, public goods ...
KONISHI Hideo, FURUSAWA Taiji
core   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Global Public Goods

Recognition of the interdependencies characterizing the Earth (a global common) and the globalization phenomenon necessitate collective actions at the global level to solve multilateral issues in trade, finance, environment, spread of infectious diseases
U. Sankar
core  

Punishing Free Riders: how group size affects mutual monitoring and the provision of public goods [PDF]

Standard game theoretic models predict, based on subgame perfection, that public goods will not be provided even if agents are allowed to monitor free riders at some cost. Further, because punishment is not credible in these environments, this prediction
Jeffrey Carpenter
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Global and regional public goods: a prognosis for collective action [PDF]

This paper applies modern concepts from the theory of public goods to indicate why progress has been made with respect to some global and regional public goods (for example, cutting sulphur emissions) but not with respect to others (for example, cutting ...
Todd Sandler
core  

Common values for common goods: a circular regeneration model for active citizenship

Techne
Regenerating cultural heritage implies adopting a systemic and multi-scalar approach capable of considering the characteristics and flows of relations between the different components of the system.
Francesca Ciampa, Martina Bosone
doaj   +1 more source