Results 111 to 120 of about 1,453,524 (301)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Stylised features of price setting behaviour in Portugal: 1992-2001 [PDF]

open access: yes
This paper identifies the empirical stylized features of price setting behaviour in Portugal using the micro-datasets underlying the consumer and the producer price indexes.
Dias, Daniel   +2 more
core  

(WP 2019-01) Stratification Economics as an Economics of Exclusion [PDF]

open access: yes, 2019
Stratification Economics (SE) is an emergent sub-field in economics, but its JEL classification misrepresents its content and its relationship to the whole of economics.
Davis, John B.
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Crossing the Point of No Return: A Public Goods Experiment [PDF]

open access: yes
Participants in a public goods experiment receive private or common signals regarding the so-called "point of no return", meaning that if the group's total contribution falls below this point, all payoffs are reduced.
M. Vittoria Levati   +2 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The Cost of non-Maghreb: Achieving the Gains from Economic Integration [PDF]

open access: yes
The purpose of this paper is to estimate the impact of the integration of Maghreb countries into a free trade area on the main macroeconomic aggregates. By using the MIRAGE model and MacMap database, we tested different scenarios to estimate the gains or
Bchir, Hédi   +3 more
core   +1 more source

Cheater-altruist synergy in immunopathogenic ecological public goods games

open access: yes, 2017
Much research has focused on the deleterious effects of free-riding in public goods games, and a variety of mechanisms that suppresses cheating behaviour. Here we argue that under certain conditions cheating behaviour can be beneficial to the population.
Morsky, Bryce, Vural, Dervis Can
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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