Results 141 to 150 of about 5,193,989 (225)

Polymer Concepts in Cellular Function

Advanced Science, EarlyView.
Miao Yu, Shikha Dhiman, Dorothee Dormann, Frauke Gräter, Katja Luck, Friederike Schmid, Andreas Walther, Edward A. Lemke   +7 more
wiley   +1 more source

Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor‐Binding and Non‐Canonical Assembly Sites

Advanced Science, EarlyView.
Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke, Xin Li, Xiaoli Wang, Zhaoxia Huang, Shaojie Xue, Yuyang Liu, Jing Pan, Guowei Hu, Yayu Wang, Cheng Wang, Shoudeng Chen   +10 more
wiley   +1 more source

Programmable Sequential 4D Actuation in Multistable Kirigami Metamaterials

Advanced Science, EarlyView.
This study presents a modular kirigami metamaterial framework enabling programmable multistability and sequential 4D actuation. By coupling geometry‐controlled multistability with material‐dependent recovery kinetics, spatiotemporal deformation can be precisely programmed.
Eui‐Hyun Kim, Minsung Kim, Hyunsik Yoon, Keun Park   +3 more
wiley   +1 more source

Adult-onset IgA Vasculitis Initially Attributed to a Cutaneous Drug Reaction and Diverticulitis. [PDF]

J Community Hosp Intern Med Perspect
Tou LC, Hobayan CGP, Devine S, Koraym S.
europepmc   +1 more source

Lattice Chloride Shielding and Reconstructed Phosphate Armor for Stable Seawater Electrolysis

Advanced Science, EarlyView.
A dual‐protection strategy integrating lattice Cl shielding with dynamically reconstructed phosphate armor enables selective OH adsorption and suppresses chloride‐induced corrosion during alkaline seawater electrolysis, delivering durable operation at industrial‐level current densities.
Yatao Yan, Yuxing Lin, Xing Chen, Shuo Yang, Ke Zhou, Jifang Chen, Lubin Ni, Ming Chen   +7 more
wiley   +1 more source

Early midazolam exposure and short-term risk of acute exacerbation of COPD in critically ill patients: a target trial emulation using the MIMIC-IV database. [PDF]

Front Artif Intell
Qin G, Zou K.
europepmc   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source

The next evolution of theranostics: from target discovery to integrated precision medicine. [PDF]

Front Med (Lausanne)
Montemagno C, Serrano B, Paulmier B.
europepmc   +1 more source

Carbohydrate‐Mediated Cellular Uptake of Boronic Acid Hybrids In Cellulo and Insulin‐Deficient Zebrafish: Live Imaging and Application of Multiphoton FLIM

Advanced Science, EarlyView.
Boronic acid‐based fluorescent hybrids have been used as part of a versatile platform for real‐time metabolic bioimaging across cellular and organismal scales. Including glucose‐responsive imaging in living cells and in an insulin‐deficient vertebrate model, this work opens new opportunities for the development of precision diagnostics, metabolic ...
Haobo Ge, John S. Fossey, David Gonzalez Calatayud, Stephen E. Flower, Sabrina Wang, Hanna Aitessaid, Melita Tvardauskaite, Julia Dudzic, Max Jewell, Charareh Pourzand, Stanley W. Botchway, David Gurevich, Tony D. James, Sofia I. Pascu   +13 more
wiley   +1 more source

Hidden Hollows of the Fetal Cranium-Lacunar Skull in Isolation. [PDF]

Case Rep Obstet Gynecol
Noonan G, Sheahan L, Sterrett M.
europepmc   +1 more source