Results 1 to 10 of about 1,604,721 (347)

Are online prediction tools a valid alternative to genomic profiling in the context of systemic treatment of ER-positive breast cancer?

Cellular & Molecular Biology Letters, 2017
Background Clinicians use clinical and pathological parameters, such as tumour size, grade and nodal status, to make decisions on adjuvant treatments for breast cancer.
Umar Wazir, Kinan Mokbel, Amtul Carmichael, Kefah Mokbel   +3 more
doaj   +1 more source

De-Escalation of Breast Cancer Surgery Following Neoadjuvant Systemic Therapy

European Journal of Breast Health, 2022
Breast cancer treatment has seen many advances in recent decades, lessening the morbidity to patients, while improving outcomes. Central to these gains has been the introduction of breast conserving surgery and neoadjuvant systemic therapy (NST).
Umar Wazir, Kefah Mokbel
doaj   +1 more source

Is Autologous Fat Grafting an Oncologically Safe Procedure following Breast Conserving Surgery for Breast Cancer? A Comprehensive Review

Journal of Investigative Surgery, 2022
Background Autologous fat grafting (AFG) is a recognized surgical procedure to correct deformities following breast conservation surgery (BCS) for breast cancer. However, there are concerns about the oncological safety of this technique. In this study we
Salim Tayeh, Samantha Muktar, Umar Wazir, Amtul. R. Carmichael, Zuhair Al-Fardan, Abdul Kasem, Moustapha Hamdi, Kefah Mokbel   +7 more
doaj   +1 more source

Modeling of GRACE-Derived Groundwater Information in the Colorado River Basin [PDF]

, 2019
Groundwater depletion has been one of the major challenges in recent years. Analysis of groundwater levels can be beneficial for groundwater management.
Ahmad, Sajjad, Kalra, Ajay, Rahaman, Md Mafuzur, Thakur, Balbhadra   +3 more
core   +2 more sources

Video-assisted self-reflection of resuscitations for resident education and improvement of leadership skills: A pilot study

Perspectives on Medical Education, 2021
Introduction One of the most challenging aspects of Emergency Medicine (EM) residency is mastering the leadership skills required during a resuscitation.
Lauren Kava, Kerin Jones, Robert Ehrman, Laura Smylie, Matthew McRae, Elizebeth Dubey, Brian Reed, Anne Messman   +7 more
doaj   +1 more source

Spontaneous Spinal Epidural Hematoma in a Patient on Apixaban for Nonvalvular Atrial Fibrillation

Case Reports in Hematology, 2020
Background. With the rise in the use of direct oral anticoagulants (DOACs), more hemorrhagic complications are being encountered. Since the first description of a case of spontaneous spinal epidural hematoma (SSEH) related to the utilization of DOACs in ...
Ahmad El Alayli, Logeswari Neelakandan, Hicham Krayem   +2 more
doaj   +1 more source

Breast Lipofilling: A Review of Current Practice

Archives of Plastic Surgery, 2015
Lipofilling is a reconstructive and aesthetic technique that has recently grown in popularity and is increasingly being used in breast surgery. Previous concerns had been raised regarding its safety when used for remodelling and reconstruction of the ...
Abdul Kasem, Umar Wazir, Hannah Headon, Kefah Mokbel   +3 more
doaj   +1 more source

Ultrasound-guided axillary vein puncture for cardiac devices implantation in patients under antithrombotic therapy

Indian Pacing and Electrophysiology Journal, 2020
Background: Ultrasound-guided axillary venous puncture (UGAVP) for cardiac devices implantation has been developed because of its rapidity, safety and potential long-term lead protection.
Mohammed ElJamili, Sok-Sithikun Bun, Decebal Gabriel Latcu, Tahar Delassi, Mustapha Elhattaoui, Nadir Saoudi   +5 more
doaj   +1 more source

Cryoglobulinemic Glomerulonephritis Presenting as Acute Kidney Injury on Chronic Kidney Disease in Rheumatoid Arthritis

Annals of Internal Medicine: Clinical Cases, 2022
Cryoglobulinemic vasculitis (CV) is one of the manifestations of rheumatoid arthritis (RA). Here, we present a case of a 69-year-old woman with uncontrolled long-standing RA who presented with heart failure exacerbation and had an incidental finding of ...
Brinda Basida, Nirav Zalavadiya, Mahesha Makandura, Malitha Hettiarachchi   +3 more
doaj   +1 more source

Preclinical pharmacology and safety studies to support an AAV9 NGLY1 gene therapy clinical trial for the treatment of NGLY1 deficiency

Molecular Therapy: Methods & Clinical Development
GS-100 is an AAV9 gene replacement therapy for the treatment of N-glycanase 1 (NGLY1) deficiency, an ultra-rare, recessive disorder characterized by developmental delay, intellectual disability, hyperkinetic movement disorder, elevated liver enzymes ...
Lei Zhu, Jennifer W. Cook, Alicia Newton, Selina S. Dwight, Brendan Beahm, Matt Wilsey, William F. Mueller, Becky Schweighardt   +7 more
doaj   +1 more source