Results 221 to 230 of about 678,091 (299)

Microfluidic Electrochemical Biosensor for the Detection of Platelet Factor 4 Antibody‐Mediated Thrombotic Disorders

Advanced Science, EarlyView.
A microfluidic electrochemical biosensor enables sensitive and specific detection of antibodies associated with vaccine‐induced immune thrombotic thrombocytopenia (VITT) and heparin‐induced thrombocytopenia (HIT). The platform uses two antigen targets— platelet factor 4 (PF4) and cross‐linked‐PF4 (c‐PF4)—and microliter volumes of patient sera to ...
Diana F. Cedillo‐Alcantar, Adam Kanack, Seonhwa Lee, Alan M. Gonzalez‐Suarez, Kihak Gwon, Emily Mauch, Thi Thanh‐Qui Nguyen, Anand Padmanabhan, Alexander Revzin   +8 more
wiley   +1 more source

Tolebrutinib for secondary progressive multiple sclerosis: A summary from the Institute for Clinical and Economic Review's California Technology Assessment Forum. [PDF]

J Manag Care Spec Pharm
Mohammed Fahim S, Lin GA, McQueen B, Zemplenyi A, Richardson M, Agboola F.   +5 more
europepmc   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Cutaneous <i>Leishmania mexicana</i> in a child: A diagnostic challenge in rural Arizona. [PDF]

JAAD Case Rep
Epino M, Druskovich C, Saglimbeni GS, Price H, Vargas de Stefano D.   +4 more
europepmc   +1 more source

Mapping Charge Interactions in Intrinsically Disordered Proteins

Advanced Science, EarlyView.
This study presents analytical models to predict intrachain distances in intrinsically disordered proteins (IDPs), accounting for charge patterning, salt concentration, and electrostatic effects. Validated against single‐molecule FRET data, a minimal‐parameter polymer model is identified that captures key interactions and chain dimensions. These models
Michael Phillips, Andrea Holla, Magdalena Wojtas, Aritra Chowdhury, Andrea Sottini, Sebastian L. B. König, Natalie Mutter, Nick Lamb, Jonathan Huihui, Monika Lopko, Andrea Soranno, Daniel Nettels, Andrzej Ożyhar, Benjamin Schuler, Kingshuk Ghosh   +14 more
wiley   +1 more source

A gap and synergy analysis of the European research infrastructure (RI) ecosystem: advancing the novel GRACE-RI dedicated to plant genetic resources. [PDF]

Ann Bot
De Paola D, Taranto F, Mousavi S, Mercati F, Sabetta W, Tumolo M, Islam S, Pieruschka R, Scaloni A, Adam-Blondon AF, Maggioni L, Goritschnig S, Guzzon F, Ianigro M, Vendramin GG, Giuliano G, Giuliano G, Bucci G.   +17 more
europepmc   +1 more source

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

Advanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló, Elisabetta Ada Cavalcanti‐Adam, Carlos Mas‐Moruno   +2 more
wiley   +1 more source

<i>Corynebacterium bovis</i> Surgical Site Infection and Abscess Formation: A Case Report. [PDF]

Clin Case Rep
VanGorder G, Peterson E.
europepmc   +1 more source

Prevalence of PD-1 Inhibitor-Associated Peripheral Neuropathy: A Retrospective Cohort Study. [PDF]

Life (Basel)
Ganji-Angirekula S, Segada NW, Hasan P, Grace PM, Wang J, Sun X, Javed S.   +6 more
europepmc   +1 more source

Mondo family proteins in diabetes. [PDF]

Front Endocrinol (Lausanne)
Barodia SK, Grant MB, Gorbatyuk MS.
europepmc   +1 more source