Results 101 to 110 of about 11,684 (217)
Modifying the common marmoset monkey (Callithrix jacchus) genome: transgenesis and targeted gene modification in vivo and in vitro [PDF]
, 2015 The most widely used animal model for biomedical research is the mouse. Yet, the physiological differences between mice and humans sometimes result in findings of questionable translational value.
Kahland, Tobias Sören
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Humanin Mitigates Aβ‐Induced Retinal Pigment Epithelium Injury via AMPK‐Beclin1‐Dependent Mitophagy
Aging Cell, Volume 25, Issue 7, July 2026.Humanin (HN) enhanced the clearance of Aβ‐accumulated mitochondria in the RPE while preserving retinal function and RPE barrier integrity. HN activated AMP‐activated protein kinase (AMPK), leading to phosphorylation of ULK1 and Beclin1, which promoted the interaction between Beclin1 and Parkin and their translocation to mitochondria.
Ha Young Jang +7 more
wiley +1 more source
Challenge to hand-rear of the common marmoset [PDF]
, 2019 In mid July 2018, the common marmoset bred in Okayama University gave birth to a triplet. It is very difficult to raise three infants. We selected the most heaviest one of her siblings, and we call her “POCKE”. We brought her up on the bottle for 80 days
Hashimoto, Haruna
core
Journal of Neurochemistry, Volume 170, Issue 7, July 2026.The exceptional size of the human cerebral cortex reflects evolutionary changes in neural precursors (NPs), the cells that generate cortical neurons and glia. Pluripotent stem cell‐derived brain organoids now allow direct comparison of human, nonhuman primate, and rodent in the laboratory.
Wendy W. Y. Choi, Julien Muffat, Yun Li
wiley +1 more source
Cellular organization of adult neurogenesis in the Common Marmoset. [PDF]
, 2010 peer reviewedAdult neurogenesis within the subgranular zone (SGZ) of the hippocampal dentate gyrus and the subventricular zone (SVZ) of the lateral ventricle (LV) has been most intensely studied within the brains of rodents such as mice and rats. However,
Hermann, Sven +11 more
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Viral Diseases of Common Marmosets
, 2019 Common marmosets are highly susceptible to several viral pathogens that exist as latent or subclinical infections in their natural reservoir hosts but cause severe disease or death when interspecies transmission occurs. Examples of such viruses in marmosets are herpes simplex virus infections, parainfluenza virus 1 infections, and measles acquired from
Mätz-Rensing, Kerstin, Bleyer, Martina
openaire +1 more source
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +1 more source
Data_Sheet_1_A reappraisal of the default mode and frontoparietal networks in the common marmoset brain.DOCX [PDF]
In recent years the common marmoset homolog of the human default mode network (DMN) has been a hot topic of discussion in the marmoset research field. Previously, the posterior cingulate cortex regions (PGM, A19M) and posterior parietal cortex regions ...
Alexander Woodward (11746781) +2 more
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Isolation and characterization of several plasma apolipoproteins of common marmoset monkey. [PDF]
, 1990 To explore the potential of the common marmoset monkey (Callithrix jacchus) as a model for human plasma lipoprotein metabolism, several marmoset apolipoproteins were isolated and characterized in this study.
K H Weisgraber +3 more
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Thioacetamide-induced hepatic fibrosis in the common marmoset
Experimental Animals, 2018 The common marmoset (Callithrix jacchus) is a nonhuman primate that is used for preclinical research on stem cell transplantation therapies due to its similarity to human beings as well as its small size, enabling researchers to perform experiments without preparing a large number of cells.
Inoue, Takashi +7 more
openaire +3 more sources