Results 81 to 90 of about 22,134 (222)

Novel Marmoset (Callithrix jacchus) Model of Human Herpesvirus 6A and 6B Infections: Immunologic, Virologic and Radiologic Characterization [PDF]

, 2013
Human Herpesvirus 6 (HHV-6) is a ubiquitous virus with an estimated seroprevalence of 95% in the adult population. HHV-6 is associated with several neurologic disorders, including multiple sclerosis, an inflammatory demyelinating disease affecting the ...
Ellis, Mary E, Gaitán, María I., Harberts, Erin, Jacobson, Steven, Leibovitch, Emily, Macri, Sheila, Maggi, Pietro, Motanic, Kelsey, Reich, Daniel S., Silva, Afonso, Westmoreland, Susan V., Wohler, Jillian E.   +11 more
core   +2 more sources

Quantitative Analysis of Locus Coeruleus Neurons and Thalamic Noradrenergic Axons in a Progressive 1‐Methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine Monkey Model of Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease is mainly characterized by dopaminergic neurodegeneration in the substantia nigra pars compacta (SNc) and α‐synuclein accumulation. The locus coeruleus (LC) is also affected in Parkinson's disease and linked to some nonmotor symptoms, but the extent and timing of its degeneration remain unclear.
Megan Carrillo, Nagore Hernández‐Pinedo, Josefa Zaldivar‐Diez, Isabel Pérez‐Santos, José A. Obeso, Carmen Cavada, Javier Blesa   +6 more
wiley   +1 more source

Generation and validation of a common marmoset embryonic stem cell line ActiCre-B1 that ubiquitously expresses a tamoxifen-inducible Cre-driver

Stem Cell Research, 2021
We previously reported the efficient targeted introduction of transgenes into the genomic DNA of the common marmoset (Callithrix jacchus) using CRISPR-Cas9. In this study, we generated a marmoset embryonic stem cell (ESC) line that ubiquitously expresses
Sho Yoshimatsu, Kanae Ohtsu, Tsukika Sato, Masafumi Yamamoto, Erika Sasaki, Seiji Shiozawa, Hideyuki Okano   +6 more
doaj   +1 more source

Mechanistic refinement of the common marmoset model for multiple sclerosis [PDF]

, 2012
Multiple sclerosis (MS) is a chronic neurological disease that affects the brain and spinal cord. It is thought that MS is an autoimmune disease, where a person’s immune system reacts to its own body, namely the myelin sheath that surrounds the nerve
Jagessar, S.A. (Anwar)
core   +2 more sources

Novel Primate Model of Serotonin Transporter Genetic Polymorphisms Associated with Gene Expression, Anxiety and Sensitivity to Antidepressants [PDF]

, 2016
This is the final version of the article. It first appeared from Nature Publishing Group via https://dx.doi.org/10.1038/npp.2016.41Genetic polymorphisms in the repeat upstream region of the serotonin transporter gene (SLC6A4) are associated with ...
A Caspi, A Caspi, A Heils, A Serretti, AJ Bennett, AJ Shackman, Andrea M Santangelo, Angela C Roberts, Anne C Ferguson-Smith, AS Kristensen, BM Bezerra, C Agustín-Pavón, C Grillon, CJ Harmer, CJ Harmer, D Marazziti, D Suri, DC Blanchard, DW Grupe, E Pascale, E Sasaki, Evelien HS Schut, G Perna, Gemma Cockcroft, GJ Carey, H Shimada, Hannah F Clarke, HP Jedema, J Amat, J Cilia, J Pacheco, JA Oler, JM Kent, JM Koolhaas, K Benirschke, K Hinkelmann, K Sawada, KL Bigos, KP Lesch, KP Lesch, L Pezawas, M Barros, M Browning, M Inoue-Murayama, M Simplicio, MF Stevenson, Mitsuteru Ito, MR Munafò, MS Ansorge, N Cross, N Lelyveld, N McNaughton, NH Kalin, P Flicek, R Keers, S Gyawali, S Porcelli, S Spinelli, SE Murphy, SF Ferrari, T Canli, X-Z Hu, Y Shiba, Yoshiro Shiba   +63 more
core   +3 more sources

Taxon, Arboreality, Sex, and Season—Factors Influencing Gastrointestinal Parasite Occurrence in Zoo‐Housed Non‐Human Primates

Zoo Biology, EarlyView.
ABSTRACT The emergence of anthelminthic resistance is a well‐documented phenomenon in livestock and companion animals. Given the scarcity of new antiparasitic drugs, the implementation of effective, holistic anthelminthic control strategies is critical to preserving the efficacy of existing treatments.
Stalder Sandro, Hatt Jean‐Michel
wiley   +1 more source

The MacBrain Resource Center (MBRC) rhesus macaque embryonic brain histology datasets

Journal of Anatomy, EarlyView.
We introduce the MacBrain Resource Center (MBRC) Collections of rhesus macaque embryonic brain tissue. Here, we illustrate histo‐ and immunohistology from our dynamically growing Collection 6, which currently contains >10,000 zoomable and downloadable images from n = 14 male and female embryos from early to late in gestation.
Valeria Mendoza‐Silva, Emma Burke, Lucy Greene, Mikhail Rodov, Janja Kopić, Phil Barello, Yury M. Morozov, Keiko Moriya‐Ito, Chiaki Ohtaka‐Maruyama, Zeljka Krsnik, Pasko Rakic, Alvaro Duque   +11 more
wiley   +1 more source

Characterization of oral microbiota in marmosets: Feasibility of using the marmoset as a human oral disease model.

PLoS ONE, 2019
With rapid aging of the world's population, the demand for research, for a better understanding of aging and aging-related disorders, is increasing. Ideally, such research should be conducted on human subjects.
Sachiko Takehara, Jorge L Zeredo, Yasuhiro Kumei, Kensuke Kagiyama, Kazumasa Fukasawa, Akiko Oshiro, Masayuki Ueno, Noriko Kojimahara, Shunsuke Minakuchi, Yoko Kawaguchi   +9 more
doaj   +1 more source

Network topology of the marmoset connectome

Network Neuroscience, 2020
The brain is a complex network of interconnected and interacting neuronal populations. Global efforts to understand the emergence of behavior and the effect of perturbations depend on accurate reconstruction of white matter pathways, both in humans and ...
Zhen-Qi Liu, Ying-Qiu Zheng, Bratislav Misic   +2 more
doaj   +1 more source

A MOSAIC of methods: Improving ortholog detection through integration of algorithmic diversity

, 2014
Ortholog detection (OD) is a critical step for comparative genomic analysis of protein-coding sequences. In this paper, we begin with a comprehensive comparison of four popular, methodologically diverse OD methods: MultiParanoid, Blat, Multiz, and OMA ...
Hernandez, Ryan D., Maher, M. Cyrus
core   +2 more sources