Results 61 to 70 of about 11,684 (217)

Use of human methylation arrays for epigenome research in the common marmoset (Callithrix jacchus) [PDF]

, 2017
tWe examined the usefulness of commercially available DNA methylation arrays designed for the humangenome (Illumina HumanMethylation450 and MethylationEPIC) for high-throughput epigenome analysisof the common marmoset, a nonhuman primate suitable for ...
Bundo, Miki, Kasai, Hidetoshi, 496460, Oh-Nishi, Arata, 496461, 496462, Iwamoto, Kazuya, Ikegame, Tempei, Zhao, Zhilei, Suhara, Tetsuya, Jinde, Seiichiro, Kasai, Kiyoko, Kato, Tadafumi, 496457, 496458, 496459, 496470, 須原 哲也, Ueda, Junko, Aiba, Atsu, Murata, Yui, 496463, 496464, 496465, 496466, 496467, 496468, 496469   +27 more
core   +1 more source

Prediction of Human Serum Concentration–Time Profiles of Golimumab and Ustekinumab Using Pharmacokinetic Data From Common Marmosets With Assessment of Anti‐Drug Antibodies

Biopharmaceutics &Drug Disposition, EarlyView.
This study identified new optimal allometric scaling exponents for human PK prediction of monoclonal antibodies with linear PKs from marmoset PK data. In addition, immunogenicity in common marmosets was evaluated following the repeated dose of golimumab and ustekinumab, minimal anti‐drug antibodies were detected.
Ayaka Tajiri, Shogo Matsumoto, Nanami Furukawa, Kensuke Kagiyama, Hiroshi Ikeda, Kazumasa Fukasawa, Hiroki Takano   +6 more
wiley   +1 more source

Variation in response behaviours in captive common marmosets (Callithrix jacchus) [PDF]

, 2006
Individual variation can be seen in many aspects of an organism, from its physical structure to its behaviour. Contributing factors to variation in behaviour may includes, age, genetic differences and even size.
Blackwood, Nicholas Simon
core  

Transgene detection from the genomic DNA of common marmoset embryos. [PDF]

, 2023
(A) PCR efficiency of the primer sets for BII (white) and APP-2A (light gray) analyzed by qPCR. Vertical and horizontal axis represent threshold cycle (Ct) values and the amount of template plasmid, respectively.
Eiko N. Minakawa (6883025), Ikuo Tomioka (121813), Mitsuo Ota (16274696), Kazuhiko Seki (301711), Hikaru Kousaku (16274699), Nanami Kohri (16274693)   +5 more
core   +1 more source

Humans are not unique: difficult birth is common in placental mammals

Biological Reviews, EarlyView.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source

Utterance evolution: the road to generative, combinatorial communicators

Biological Reviews, EarlyView.
ABSTRACT Language has long been considered uniquely complex in the animal kingdom; however, animal research over the last decade has begun to challenge some long‐standing premises about exactly which language capacities are uniquely human. The task of resolving why and how complex communication systems evolve, particularly human language, has ...
Catherine Crockford, Roman Martin Wittig, Cedric Girard‐Buttoz   +2 more
wiley   +1 more source

Evaluation of the pharmacokinetics of metformin and acarbose in the common marmoset [PDF]

Pathobiology of Aging & Age-related Diseases, 2019
Metformin has beneficial effects on several age-related diseases (e.g., diabetes, obesity, cancer) and extends lifespan in nematodes and mice. Acarbose, an FDA-approved agent for treating type 2 diabetes, prevents breakdown of complex carbohydrates. Both compounds have been suggested as potential anti-aging interventions and acarbose has been shown to ...
Fernandez, Elizabeth, Ross, Corinna, Liang, Hanyu, Javors, Martin, Tardif, Suzette, Salmon, Adam B.   +5 more
openaire   +2 more sources

Improved Post‐Processing Framework for Whole Slide Imaging and 3D Reconstruction

Microscopy Research and Technique, EarlyView.
Workflow for 3D reconstruction of marmoset whole‐slide histology. Individual tiles undergo vignette correction to address illumination artifacts before stitching into full‐section images. Sections are then reconstructed using the Possum framework, with a level‐set method incorporated at the nonlinear deformable stage to stabilize alignment and reduce ...
Emily L. De Leon Alvarado, Daryan Chitsaz, Ilana R. Leppert, Jennifer S. W. Campbell, Yangyingqi Zhou, G. Bruce Pike, Timothy E. Kennedy, Christine L. Tardif, Christopher D. Rowley   +8 more
wiley   +1 more source

Marmosets as models of infectious diseases

Frontiers in Cellular and Infection Microbiology
Animal models of infectious disease often serve a crucial purpose in obtaining licensure of therapeutics and medical countermeasures, particularly in situations where human trials are not feasible, i.e., for those diseases that occur infrequently in the ...
Ian C. T. Herron, Thomas R. Laws, Michelle Nelson   +2 more
doaj   +1 more source

Non-viral generation of marmoset monkey iPS cells by a six-factor-in-one-vector approach. [PDF]

PLoS ONE, 2015
Groundbreaking studies showed that differentiated somatic cells of mouse and human origin could be reverted to a stable pluripotent state by the ectopic expression of only four proteins.
Katharina Debowski, Rita Warthemann, Jana Lentes, Gabriela Salinas-Riester, Ralf Dressel, Daniel Langenstroth, Jörg Gromoll, Erika Sasaki, Rüdiger Behr   +8 more
doaj   +1 more source