Results 161 to 170 of about 1,260,895 (306)

Schwann Cell Synthesized Cholesterol Orchestrates Peripheral Nerve Regeneration via Structural and IGF1‐Dependent Signaling Mechanisms

open access: yesAdvanced Science, EarlyView.
This study reveals that Schwann cell FDFT1‐mediated cholesterol synthesis is essential for peripheral nerve regeneration via dual roles: as a structural component for myelin and as a metabolic signal that upregulates IGF1. IGF1 promotes axonal growth through paracrine action and enhances Schwann cell differentiation/ myelination via an intrinsic IGF1R ...
Shuyi Xu   +12 more
wiley   +1 more source

Advancing Precision Nutrition Through Multimodal Data and Artificial Intelligence

open access: yesAdvanced Science, EarlyView.
Individual responses to food vary dramatically, challenging traditional dietary advice. This review explores how the unique genetic makeup, gut microbiome, and brain activity shape host metabolic health. We examine how artificial intelligence integrates these multimodal data to predict individualized dietary needs, moving beyond one‐size‐fits‐all ...
Yuanqing Fu   +5 more
wiley   +1 more source

Post‐Translational Modifications in Animal Circadian Clocks

open access: yesAdvanced Science, EarlyView.
Circadian clocks coordinate physiology with daily environmental cycles through conserved transcriptional–translational feedback loops. This review summarizes how post‐translational modifications fine‐tune clock function, highlights the evolutionary convergence of circadian timekeeping in Drosophila and mammals, and emphasizes the central of these ...
Xianhui Liu, Yong Zhang
wiley   +1 more source

Gender and common mental disorders: A perspective from India. [PDF]

open access: yesWorld J Psychiatry
Vibha K V   +3 more
europepmc   +1 more source

Rapid and Direct Detection of Methamphetamine in Biofluids using a MXene‐Enabled Electrochemical Sensor

open access: yesAdvanced Science, EarlyView.
A MXene‐enhanced electrochemical sensor enables the rapid and direct detection of methamphetamine. Molecular simulations reveal that specific MXene surface functional groups act as key signal amplifiers by facilitating interfacial interactions. The sensor demonstrates high sensitivity and robust performance in complex biological matrices.
Ri Wang   +7 more
wiley   +1 more source

Effect Differences of Omega‐3 Fatty Acids From Plant Oil and Fish Oil on Human Health

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Omega‐3 fatty acids in plant oil is no less than fish oil on human health. ALA in plant oil takes directly healthy effects without conversion to DHA and EPA. Plant oil can be substitutes for fish oil to support partial ω‐3 fatty acids. For people who cannot afford fish oil, plant oil is also good for public health.
Mengxue Fang   +3 more
wiley   +1 more source

Patient Satisfaction With Medication Pricing in Community Pharmacy Settings: A Cross‐Sectional Study of Individuals With Comorbidities

open access: yesAGING MEDICINE, EarlyView.
The majority of patients in Malaysia purchase medications at community pharmacies for simple medical conditions. One‐fourth of them are not satisfied with the pricing practices at these pharmacies. The majority rely on medical insurance to purchase routine medications.
Amelia Ravindran   +3 more
wiley   +1 more source

Laparoscopic and Endoscopic Cooperative Surgery for Gastric Cancer as an Alternative Treatment in Elderly Patients: A Prospective Observational Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
In a prospective study of 20 elderly gastric cancer patients who declined gastrectomy, laparoscopic and endoscopic cooperative surgery (LECS) was technically safe and preserved postoperative function. However, as oncological curability cannot be assured in advanced cases, careful selection and informed consent are essential.
Marie Washio   +9 more
wiley   +1 more source

Prevention of Common Mental Disorders

open access: yesPsychology and Psychotherapy Research Study, 2022
openaire   +1 more source

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