Results 41 to 50 of about 590,887 (261)

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The relationship between asthma and common mental health disorders: depression and anxiety disorders

open access: yesAlergologia Polska
Asthma is a chronic, inflammatory respiratory disease characterised by reversible airflow limitation and airway hyperresponsiveness. It affects over 300 million people worldwide and has a negative impact on patients’ quality of life.
Natalia Krupińska   +3 more
doaj   +1 more source

Long-term disability in common mental disorders in Chinese community: evidence from a five-year follow-up study

open access: yesBMC Psychiatry, 2022
Background Common mental disorders are general term for mental disorders with high disability rates and significant social burden. The purpose of this study was to determine the degree of long-term disability associated with common mental disorders and ...
Yijiao Zhang   +17 more
doaj   +1 more source

Common mental disorders: falling through the gap [PDF]

open access: yesThe Lancet Psychiatry, 2019
People with mental illness are more likely than the rest of the population to have physical health problems and to die prematurely. The Lancet Psychiatry Commission on protecting physical health in people with mental illness draws attention to this global inequality.
Lewis, G, Hayes, J
openaire   +3 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Prevention for common mental disorders in low-resource settings

open access: yesIndian Journal of Social Psychiatry, 2017
Only a limited research evidence is available from low- and middle-income countries for various preventive strategies for anxiety and mood disorders. In the context of these low-resource settings, the models of primary and secondary prevention have to be
Raman Deep Pattanayak
doaj   +1 more source

Therapists’ prototypes of common mental disorders – An empirical identification

open access: yesPsychiatry Research Communications, 2023
Background: Although earlier studies concluded that clinicians' prototypes of patients with mental disorders can influence diagnostic decisions, it remains unclear how presumably more or less prototypical features were identified in these studies ...
Svea Kröber   +7 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Common Mental Disorders

open access: yes, 2016
Psychological disorders cause a considerable proportion of long-term sickness absence and constitute the most significant reason for disability pensions of employees under 55 years of age. Knowledge of the risk factors will help occupational physicians to initiate treatments and interventions at an early stage thereby preventing long term sickness ...
Stansfeld, S   +5 more
openaire   +3 more sources

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