Results 121 to 130 of about 842,699 (351)

Circuit transients due to negative bias arcs on a high-voltage solar array in low Earth orbit [PDF]

Arcing to negatively biased, exposed solar cell interconnects on solar arrays placed in plasma environments was established. Arcing, however, may cause damaging interference with the operation of electrical power systems in spacecraft planned to be ...
Metz, R. N.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A Three-Vector Fast Model Predictive Control Method for Steady State Performance Improvement

IEEE Access
A fast three-vector model predictive control method based on an improved H8 inverter is proposed for the Permanent Magnet Synchronous Motor (PMSM) driven by a two-level three-phase voltage source inverter.
Yongzhen Zhang, Pu Cheng, Kai Shen, Weiming He, Di Nian, Jun Pan   +5 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Common-mode voltage suppression for traction drive systems based on carrier phase shift control

机车电传动
To suppress the common mode voltage generated by the traction system due to inverter pulse-width modulation (PWM) and to reduce electrical corrosion of the bearings and electromagnetic compatibility (EMC) interference, this paper proposes a strategy for ...
ZHANG Ying, WANG Chenfan, CHEN Ke, HU Xian, HOU Zhaowen, WANG Wentao   +5 more
doaj  

Common Mode Voltage Removal using New Balancing Technique for Extraction of Low Level Differential Signals Embedded in Large Common Mode Voltages

International Journal of Engineering and Advanced Technology, 2019
The paper proposes a method based on new principle for removal of common mode voltages (CMVs) present in the differential signals #. These CMVs can be reduced nearly to zero without using any components with tight tolerances which is achieved using a new balancing technique.
Nilima Warke, J. M. Nair, P. P. Vaidya
openaire   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Simulation Research on Zero-vector PWM Common-mode Voltage Suppression for Clamped Five-level Converters

Kongzhi Yu Xinxi Jishu, 2018
Although more and more common-mode voltage suppression methods have been adopted for high power multi-level converter, the common-mode voltage has not been completely removed.
LI Yinling
doaj