Results 51 to 60 of about 4,981,855 (247)

Longitudinal Single‐Axon‐Resolution Imaging of Peripheral Nerve Injury Response in Mice Using an Optical Window Implant

Advanced Science, EarlyView.
A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky, Emma Anisman, Ron Perez, Sophia Zhang, Morgan Hoffman, Daniel Hunter, Abigail Cherian, Jevon Bonner, Emilia Feria, Ahmed Ahmed, Muneeb Malik, Junwei Du, Leland C. Sudlow, David M. Brogan, Matthew D. Wood, Mikhail Y. Berezin   +15 more
wiley   +1 more source

Compound Nerve Action Potential of Common Peroneal Nerve and Sural Nerve Action Potential in Common Peroneal Neuropathy

Journal of Korean Medical Science, 2008
To enhance the accuracy for determining the precise localization, the findings of the compound nerve action potentials (CNAPs) of the common peroneal nerve (CPN) were investigated in patients with common peroneal mononeuropathy (CPM) in the knee, and the sural sensory nerve action potentials (SNAPs) were also analyzed.
Kwon, Hee Kyu, Kim, Lina, Park, Yoon Keun   +2 more
openaire   +2 more sources

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

Advanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi, Lin Yang, Kang‐Li Wang, Hui‐Zhu Liu, Rui‐Ying Chen, Min Su, Xiao Xiao, Yu‐Qiu Zhang   +7 more
wiley   +1 more source

Bilateral ganglion cyst of the common peroneal nerve.

, 2002
Ganglion cysts of the common peroneal nerve are rarely described in the literature and a bilateral lesion has not been previously reported. We present a case of a 41-year-old man with a bilateral cyst of the common peroneal nerve diagnosed with ...
Armaroli S, Cusmano F, Rinaldi E, Pavone P., POGLIACOMI, Francesco, Pedrazzini M   +5 more
core   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

TRPC3‐Driven Calcium Microdomains Instruct Peripheral Nerve Regeneration With Protective Implications for Central Neurons

Advanced Science, EarlyView.
How localized Ca2+ signals orchestrate neural repair remains unclear. Here, we show that TRPC3‐driven calcium microdomains direct nerve repair by coupling spatially confined Ca2+ signals to axon regeneration. This module operates in injured peripheral neurons and correlates with neuroprotection in Parkinson's disease, revealing a spatial logic for ...
Yu Lu, Jianbo Zhao, Zhenli Xie, Yuan Wang, Ruolin Wang, Bianbian Wang, Chuhan Shen, Yali Chen, Jingyu Yao, Ziyang Li, Huadong Xu, Zuying Chai, Zhuoyu Zhang, Changhe Wang, Rong Huang   +14 more
wiley   +1 more source

A microcontroller system for investigating the catch effect: Functional electrical stimulation of the common peroneal nerve

, 2006
Correction of drop foot in hemiplegic gait is achieved by electrical stimulation of the common peroneal nerve with a series of pulses at a fixed frequency.
Wood, D E, Chappell, P H, Hart, D J, Taylor, P N   +3 more
core   +1 more source

Revitalizing the common peroneal function index for assessing functional recovery following nerve injury

Brain and Behavior, 2021
Background and Aims Peripheral nerve injury is common with poor functional recovery and consequent high personal and societal costs. Sciatic nerve transection and assessment of recovery using sciatic functional index (SFI) are widely used.
Calder Fontaine, Eric A. Yeager, Michael Sledziona, Amanda K. Jones, Jonathan Cheetham   +4 more
doaj   +1 more source

Biomimetic 3D Tactile Sensor System With Neuromorphic Encoding for Fascicle‐Level Feedback

Advanced Intelligent Systems, EarlyView.
A 3D biomimetic tactile sensor system converts skin‐like mechanical interactions into neural stimulation‐ready spike patterns. Embedded slow‐ and fast‐adapting sensors distinguish sustained pressure from transient touch, while neuromorphic encoding preserves their temporal signatures.
Minseok Kim, Jaeu Park, Minseok Kang, Yongwoo Kim, Sanghoon Lee   +4 more
wiley   +1 more source

Arthroscopic Bioabsorbable Fixation Achieves Favorable Outcomes for Unstable Knee Osteochondritis Dissecans Lesions Compared With Open Fixation and Metal Implants: A Systematic Review

Arthroscopy, EarlyView.
Purpose To systematically review studies evaluating the outcomes, complication rates, and revision rates among open, arthroscopic, and combined internal fixation techniques for unstable osteochondritis dissecans lesions of the knee, with specific attention to implant type and skeletal maturity.
Harrison S. Fellheimer, Gaston Davis, Christian McCormick, Mark Samuel, William L. Justice, Kevin B. Freedman   +5 more
wiley   +1 more source