Results 101 to 110 of about 9,029,502 (230)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Normalized Power Prior Bayesian Analysis [PDF]
The elicitation of power prior distributions is based on the availability of historical data, and is realized by raising the likelihood function of the historical data to a fractional power. However, an arbitrary positive constant before the like- lihood
Keying Ye, Yuyan Duan
core
The uses and abuses of personal UAS
, 2014 Nano UAVs promise much in terms of enhanced personal reconn aissance capabilities. But according to Dr Stephen Prior, there are a number of drawbacks to small multi-rotor aircraft, and the cost of procuring them is still relatively high.
Prior, Stephen D.
core +1 more source
Signaling Without Common Prior: An Experiment [PDF]
The common prior assumption is pervasive in game-theoretic models with incomplete information. This paper investigates experimentally the importance of inducing a common prior in a two-person signaling game. For a specific probability distribution of the
Michalis Drouvelis +2 more
core +3 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
THEPOSITIVEFOUNDATIONOFTHE COMMON PRIOR ASSUMPTION
, 2003 The existence of a common prior is a property of the state space used to model the players ’ incomplete information. We show that this property is not just a technical artifact of the model, but that it is immanent to the players ’ beliefs.
Heifetz, Aviad, Aviad Heifetz
core
Common Statement on Prior Publication Policy
Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2002 doaj +1 more source
Substantial weight gains are common prior to treatment-seeking in obese patients with binge eating disorder. [PDF]
Compr Psychiatry, 2013 Masheb RM, White MA, Grilo CM.
europepmc +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source