Results 71 to 80 of about 9,029,502 (230)
Common Knowledge and Disparate Priors: When it is O.K. to Agree to Disagree [PDF]
Abandoning the oft-presumed common prior assumption, partitioned type spaces with disparate priors are studied. It is shown that in the two-player case, a unique fundamental pair of priors can be identified in each type space, from whose properties ...
Hellman, Ziv
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 1990 "A.T. (Tom) Prior 12 Squadron R.A.A.F. Darwin & Batchelor Dec 1941 - 1943."A.T. (Tom) Prior. 12 Squadron, Royal Australian Air Force. Darwin & Batchelor.
Prior, A. T.
core
Prior elicitation in Bayesian quantile regression for longitudinal data [PDF]
, 2011 © 2011 Alhamzawi R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original auhor and source are ...
Alhamzawi, Rahim +7 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Scientific ReportsOpen common bile duct exploration (CBDE) for extrahepatic stones results in prominent abdominal scarring and substantial tissue trauma. Laparoscopic exploration offers minimal invasiveness and faster recovery and has proven superior to staged procedures;
Xiaohang Niu +7 more
doaj +1 more source
Journal of Craniovertebral Junction and SpineStudy Design: This was a retrospective cohort study. Objective: The objective of this study was to evaluate the impact of prior chemotherapy and/or radiation on outcomes among patients undergoing surgery for spinal metastases. Summary of Background Data:
Alec Giakas +14 more
doaj +1 more source