Results 21 to 30 of about 313,173 (266)

Prediction of metabolic flux distribution from gene expression data based on the flux minimization principle. [PDF]

open access: yesPLoS ONE, 2014
Prediction of possible flux distributions in a metabolic network provides detailed phenotypic information that links metabolism to cellular physiology. To estimate metabolic steady-state fluxes, the most common approach is to solve a set of macroscopic ...
Hyun-Seob Song   +2 more
doaj   +1 more source

Factor analysis models for structuring covariance matrices of additive genetic effects: a Bayesian implementation

open access: yesGenetics Selection Evolution, 2007
Multivariate linear models are increasingly important in quantitative genetics. In high dimensional specifications, factor analysis (FA) may provide an avenue for structuring (co)variance matrices, thus reducing the number of parameters needed for ...
Gianola Daniel, de los Campos Gustavo
doaj   +1 more source

Polysaccharide responsiveness is not biased by prior pneumococcal-conjugate vaccination. [PDF]

open access: yesPLoS ONE, 2013
Polysaccharide responsiveness is tested by measuring antibody responses to polysaccharide vaccines to diagnose for humoral immunodeficiency. A common assumption is that this responsiveness is biased by any previous exposure to the polysaccharides in the ...
Jens Magnus Bernth-Jensen   +1 more
doaj   +1 more source

Spatial Surface Reflectance Retrievals for Visible/Shortwave Infrared Remote Sensing via Gaussian Process Priors

open access: yesRemote Sensing, 2022
Remote Visible/Shortwave Infrared (VSWIR) imaging spectroscopy is a powerful tool for measuring the composition of Earth’s surface over wide areas. This compositional information is captured by the spectral surface reflectance, where distinct shapes and ...
Daniel Zilber   +5 more
doaj   +1 more source

Genetic Variants Detection Based on Weighted Sparse Group Lasso

open access: yesFrontiers in Genetics, 2020
Identification of genetic variants associated with complex traits is a critical step for improving plant resistance and breeding. Although the majority of existing methods for variants detection have good predictive performance in the average case, they ...
Kai Che   +6 more
doaj   +1 more source

Signaling without common prior: An experiment [PDF]

open access: yes, 2009
The common prior assumption is pervasive in game-theoretic models with incomplete information. This paper investigates experimentally the importance of inducing a common prior in a two-person signaling game. For a specific probability distribution of the
Müller, Wieland   +9 more
core   +1 more source

End-to-End Convolutional Autoencoder for Nonlinear Hyperspectral Unmixing

open access: yesRemote Sensing, 2022
Hyperspectral Unmixing is the process of decomposing a mixed pixel into its pure materials (endmembers) and estimating their corresponding proportions (abundances).
Mohamad Dhaini   +3 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters   +17 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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