Results 21 to 30 of about 406,513 (211)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The Ranking Problem of Alternatives as a Cooperative Game
, 2015 This paper considers the ranking problem of candidates for a certain position based on ballot papers filled by voters. We suggest a ranking procedure of alternatives using cooperative game theory methods.
Kondratev, Aleksei, Mazalov, Vladimir
core +1 more source
Semantic keyword search for expert witness discovery [PDF]
, 2011 In the last few years, there has been an increase in the amount of information stored in semantically enriched knowledge bases, represented in RDF format. These improve the accuracy of search results when the queries are semantically formal.
Sitthisarn, S, Lau, LMS, Dew, PM
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
The distribution of trimoraic syllables in German and English as evidence for the phonological word [PDF]
, 2013 In the present article I discuss the distribution of trimoraic syllables in German and English. The reason I have chosen to analyze these two languages together is that the data in both languages are strikingly similar.
Hall, Tracy A.
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Common Aims, Values And Principles Of Intellectual Property, Right To Competence And Others Rights
Ius Humani, 2013 This paper aims the definition of which are the pourposes, values and common principles of intellectual property, competence law of advertising, consumer and information.
Juan Carlos Riofrío Martínez-Villalba
doaj
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Evaluating Variable-Length Multiple-Option Lists in Chatbots and Mobile Search
, 2019 In recent years, the proliferation of smart mobile devices has lead to the gradual integration of search functionality within mobile platforms. This has created an incentive to move away from the "ten blue links'' metaphor, as mobile users are less ...
Bocklisch T. +8 more
core +1 more source