Results 161 to 170 of about 2,216,425 (306)

Measures to strengthen international biosafety and biosecurity practices. [PDF]

PLoS Biol
Decroly E, Berche P, Asy A, Bartlett ML, Szekely Björndal Å, Brechot C, Casey PG, Couvreur P, Espona MJ, Filippone C, Iskandriati D, James W, Marques RE, Shinwari ZK, Pályi B, Perkins D, Summermatter K, Vandenberg O, Zatloukal K, Ewbank J.   +19 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Practical guide to statistical reporting in optical imaging. [PDF]

Neurophotonics
Cheng X, Stephen EP, Yücel MA.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Outcome Reporting in Distal Radius Fracture Research: A Systematic Review Across Treatment Modalities. [PDF]

Hand (N Y)
Blum E, Perugini JM, Mologne MS, Dy CJ.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Predicting vesicoureteral reflux outcomes using artificial intelligence: A critical appraisal using APPRAISE-AI. [PDF]

PLOS Digit Health
Khondker A, Kaushal S, Wu J, Gupta N, Kwong JC, Li T, Erdman L, Rickard M, Lorenzo AJ.   +8 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

QT-related adverse events with ondansetron and olanzapine: a real-world FAERS analysis with implications for oncology anti-emetic practice. [PDF]

Front Pharmacol
Gandhi A, Parhizgar A, Bhise V.
europepmc   +1 more source

An evaluation of the effect of the Common Reporting Standard on cross-border tax evasion

, 2023
Omfanget og konsekvensene av skatteunndragelse på tvers av landegrensene vekker stor bekymring blant politiske beslutningstakere, og i løpet av de siste to tiårene har det blitt iverksatt betydelige tiltak for å fremme internasjonal skattetransparens.
openaire   +1 more source