Results 121 to 130 of about 698 (301)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

From the Cancer Stage of Capitalism to the Political Principle of the Common: The Social Immune Response of "Food as Commons". [PDF]

Int J Health Policy Manag, 2021
Rose N.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Commoning: Creating a new socio-economic order? A grounded theory study

, 2014
Interest in the commons, a concept that extends back to antiquity, has peaked in recent years as alarming resource depletion and intellectual property restrictions have caused international concern, while the Internet has increasingly linked people ...
Thompson, Randal Joy
core  

The COMmons Places ASSessment (COMPASS) Framework for the Governance of Common Goods: A Comparison of Evolving Practices

Land
In recent years, the concept of the commons has gained relevance across academic, legal and civic spheres as an alternative framework for managing shared resources.
Maria Cerreta, Fabrizia Cesarano, Stefano Cuntò, Laura Di Tommaso, Ludovica La Rocca, Caterina Loffredo, Sveva Ventre, Piero Zizzania   +7 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Urban commoning practices as a response to gender-based violence in the urban space : the experiences of the city of women in Rome

DOTTORATOIl lavoro di ricerca, a partire dal riconoscimento delle crescenti disuguaglianze che caratterizzano lo spazio urbano, le forme di pluralizzazione del pubblico e dei valori , la crisi del rapporto tra istituzioni e cittadini e le difficoltà di ...
de Strobel de Haustadt E Schwanenfeld, Lorenzo
core  

Raging Against the "Neoliberal Hellscape": Anger, Pride, and Ambivalence in Civil Society Responses to the COVID-19 Pandemic in the USA. [PDF]

Antipode, 2022
Leap B, Stalp MC, Kelly K.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Visualizando o commoning urbano: Geografias de precariedade, resistência e esperança [PDF]

In this visual essay we draw on photographs from several urban locations across Northern and Southern geographies, particularly focused on the research contexts that are explored within the papers in this Special Issue, to explore the manifold meanings,
Scheba, Suraya, Escobar, Luisa, Lages, Joana Pestana, Abbadie, Lucía, Wilhelm-Solomon, Matthew, Sanchez-Betancourt, Diana, Scheba, Andreas, Sanchez-Bajo, Claudia, Saaristo, Saila-Maria   +8 more
core   +1 more source