Results 161 to 170 of about 698 (301)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Introduction: Strategic entanglements - un/commoning as relational labour of articulating resource modalities. [PDF]

Crit Anthropol
Streinzer A, Tošić J.
europepmc   +1 more source

Covid-19: The cultural constructions of a global crisis. [PDF]

Int J Cult Stud, 2022
Frosh P, Georgiou M.
europepmc   +1 more source

Common processing plan

Prototype for Interfaces for economic databases (2.3) /bio-physical databases (2.4)/large scale data (2.5)/current models (2.6)
openaire   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Plural and commoning? Forecasting four scenarios for ethnobiology and ethnomedicine by 2035. [PDF]

J Ethnobiol Ethnomed
Pieroni A, Alrhmoun M, Sulaiman N.
europepmc   +1 more source

The Political Economy of Healthy and Sustainable Food Systems: An Introduction to a Special Issue. [PDF]

Int J Health Policy Manag, 2021
Baker P, Lacy-Nichols J, Williams O, Labonté R.   +3 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Urban digital twins: Digital twins for participatory steering. [PDF]

New Media Soc
Dawkins O, Kitchin R.
europepmc   +1 more source