Results 61 to 70 of about 317,506 (294)
We Cannot Win the Access to Medicines Struggle Using the Same Thinking That Causes the Chronic Access Crisis [PDF]
Health and Human Rights, 2020 The inequity in access to COVID-19 vaccines that we are witnessing today is yet another symptom of a pharmaceutical economy that is not fit for purpose.
Gaëlle Krikorian, Els Torreele
doaj
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Principales zonas mineras en la segunda mitad del siglo XVIII
Investigaciones Geográficas, 1989 In this work are located the most important mine areas in New Spain at the end of the colonial period in wich you can notice the influence this areas had in the settlements of the New Spain territory.
Áurea Commons de la Rosa
doaj +1 more source
‘Common things are common’ [PDF]
QJM: An International Journal of Medicine, 2017 M Razmi T, R V Nampoothiri, S Dogra
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Communications Earth & EnvironmentChlorofluorocarbons (CFCs) and carbon tetrachloride (CCl4) are ozone-depleting substances with high radiative efficiencies; however, uncertainties in their atmospheric lifetimes hinder top-down emission monitoring efforts.
Stephen Bourguet +2 more
doaj +1 more source
La minería en Nueva España en el siglo XVIII
Investigaciones Geográficas, 1988 In this paper is noted the decrease in mining in New Spain since the 17th century until de first half of the 18th century and the impel the Spanish Crown gave to the most importante industry at that time in the second half of this century.
Aurea Commons de la Rosa
doaj +1 more source
, 2023 Creativity is often conceived in terms of insight, innovation, and invention realized through technical mastery and skill. Challenging this individualistic model are “inventions” like writing, something that surely gave no clue to the form it would ultimately take—script—or the ways in which it would reorganize behaviors and brains in the cognitive ...
openaire +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source