Results 81 to 90 of about 6,508,204 (342)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Bayesian modeling of HFC production pipeline suggests growth in unreported CFC by-product and feedstock production

Nature Communications
Observationally-derived emissions of ozone depleting substances must be scrutinized to maintain the progress made by the Montreal Protocol in protecting the stratospheric ozone layer.
Stephen Bourguet, Megan Lickley
doaj   +1 more source

Investigating Social Vulnerability to Extreme Heat: Heat Islands and Climate Shelters in Urban Contexts: The Case of Bologna

ISPRS International Journal of Geo-Information
In this article we present three instruments: (1) a social vulnerability to extreme heat index to identify the areas of a city (and populations thereof) more vulnerable to extreme heat due to climate change (heat islands); (2) a new overall fragility ...
Elisa Maccabiani, Munazza Usmani, Riccardo Nanni, Maurizio Napolitano   +3 more
doaj   +1 more source

Surveying Wildlife in the Chilterns [PDF]

, 2014
This guide grew out of a series of workshops for volunteers within the Chilterns Commons Project. It focuses on surveying wildlife on particular sites, such as the Chiltern commons, rather than surveying across the wider landscape, but we hope that the ...
Harvey, Martin
core  

Common Genetic Variants Explain the Majority of the Correlation Between Height and Intelligence : The Generation Scotland Study [PDF]

, 2014
Creative Commons Attribution LicensePeer reviewedPublisher ...
Archie Campbell, B Benyamin, BH Smith, BH Smith, C Gale, Caroline Hayward, CM Calvin, CM Calvin, CM Haworth, CM Lee, D Wechsler, D Wechsler, David J. Porteous, E Whitley, G Davies, G. David Batty, GD Batty, Ian J. Deary, IJ Deary, IJ Deary, J Yang, J Yang, JC Raven, JM Starr, JM Sundet, JP Beauchamp, K Silventoinen, K Silventoinen, KL Gunderson, LJ Whalley, Lynne J. Hocking, M Trzaskowski, MC Keller, MD Lezak, Peter M. Visscher, Riccardo E. Marioni, S Macgregor, SH Lee, Shona M. Kerr, SM Kerr, TA Paajanen   +40 more
core   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Gestación y nacimiento de un estado: Guerrero

Investigaciones Geográficas, 2003
Este trabajo presenta la creación del estado de Guerrero como entidad federativa de nuestro país, y los cambios territoriales que ha sufrido desde la época prehispánica hasta la actualidad.
Áurea Commons
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Análisis comparativo de la población de la cuidad de México según censos de población 1930 - 1950 - 1970

Investigaciones Geográficas, 1971
This paper presents in an objective way the changes in geographic–economic and social–geographic structures in Chile. It analyzes the growth of the population and some of its reprecussions: Educational Reform; unemployment: Chilean Agrarian Reform; the ...
Áurea Commons de la Rosa
doaj   +1 more source

On the use of computer‐assistance to facilitate systematic mapping

Campbell Systematic Reviews, 2020
The volume of published academic research is growing rapidly and this new era of “big literature” poses new challenges to evidence synthesis, pushing traditional, manual methods of evidence synthesis to their limits.
Neal R. Haddaway, Max W. Callaghan, Alexandra M. Collins, William F. Lamb, Jan C. Minx, James Thomas, Denny John   +6 more
doaj   +1 more source