Results 81 to 90 of about 3,265,734 (307)

‘Common things are common’ [PDF]

open access: yesQJM: An International Journal of Medicine, 2017
M Razmi T, R V Nampoothiri, S Dogra
openaire   +2 more sources

Data-driven tools for optimizing urban tree planting strategies

open access: yesCity and Environment Interactions
In this study, we propose a universally applicable, two-level approach aimed at optimizing both tree planting locations and species selection, integrating the model into an intuitive Web Application.
Luca Maccacaro   +4 more
doaj   +1 more source

Concern noted: a descriptive study of editorial expressions of concern in PubMed and PubMed Central

open access: yesResearch Integrity and Peer Review, 2017
Background An editorial expression of concern (EEoC) is issued by editors or publishers to draw attention to potential problems in a publication, without itself constituting a retraction or correction.
Melissa Vaught   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

HELIN Digital Commons Committee minutes for 4/18/06

open access: yes, 2006
Minutes of the Digital Commons Committee of the HELIN Consortium for April ...
HELIN Consortium. Digital Commons Committee   +1 more
core  

From Targets to Action: Rolling up our Sleeves after Paris

open access: yesGlobal Challenges, 2017
At the United Nations Climate Change Conference in Paris in 2015 ambitious targets for responding to the threat of climate change have been set: limiting global temperature increase to “well below 2 °C […] and to pursue efforts to limit the temperature ...
Brigitte Knopf   +5 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

HELIN Digital Commons Committee minutes for 1/16/07

open access: yes, 2006
Minutes of the Digital Commons Committee of the HELIN Consortium for January ...
HELIN Consortium. Digital Commons Committee   +1 more
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy