Results 91 to 100 of about 6,508,204 (342)

Creative Gardens: Towards Digital Commons [PDF]

open access: yes, 2016
date-added: 2015-03-04 03:12:21 +0000 date-modified: 2015-04-01 06:49:53 +0000date-added: 2015-03-04 03:12:21 +0000 date-modified: 2015-04-01 06:49:53 +0000This work was supported by the Arts and Humanities Research Council, CreativeWorks London Hub ...
Briscoe, G, Lockwood, J
core  

Parasitic copepods from Egyptian Red Sea fishes: Bomolochidae Claus, 1875 [PDF]

open access: yes, 2016
© The Author(s) 2015 Open Access - This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in
A Brian   +19 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The Tragedy of the Grabbed Commons: Coercion and Dispossession in the Global Land Rush

open access: yes, 2017
Rural populations around the world rely on small-scale farming and other uses of land and natural resources, which are often governed by customary, traditional, and indigenous systems of common property.
J. Dell’Angelo   +3 more
semanticscholar   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

UNRAVELING THE ARCHITECTURE OF THE DORSAL RAPHE SYNAPTIC NEUROPIL USING HIGH-RESOLUTION NEUROANATOMY

open access: yesFrontiers in Neural Circuits, 2014
The dorsal raphe nucleus (DRN), representing the main source of brain’s serotonin, is implicated in the pathophysiology and therapeutics of several mental disorders that can be debilitating and life-long including depression, anxiety and autism.
Mariano eSoiza-Reilly   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

‘ExcelL on Campus’: Using Peers to Help International Students Negotiate Their New Learning Environment

open access: yesJANZSSA, 2012
International education is commonplace now, and Australian and New Zealand universities have many international students on their campuses. However, good practice—in terms of orienting, advising, and skill development for these students—is still far from
Karen Commons
doaj  

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