Results 111 to 120 of about 6,508,204 (342)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Principales zonas mineras en la segunda mitad del siglo XVIII

open access: yesInvestigaciones Geográficas, 1989
In this work are located the most important mine areas in New Spain at the end of the colonial period in wich you can notice the influence this areas had in the settlements of the New Spain territory.
Áurea Commons de la Rosa
doaj   +1 more source

Preventative therapies for healthy women at high risk of breast cancer [PDF]

open access: yes, 2014
Licensed under the Creative Commons Attribution Non-Commercial ...
Sestak, I
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

We Cannot Win the Access to Medicines Struggle Using the Same Thinking That Causes the Chronic Access Crisis [PDF]

open access: yesHealth and Human Rights, 2020
The inequity in access to COVID-19 vaccines that we are witnessing today is yet another symptom of a pharmaceutical economy that is not fit for purpose.
Gaëlle Krikorian, Els Torreele
doaj  

John R. Commons, Wesley N. Hohfeld and the Origins of Transactional Economics [PDF]

open access: yes
The aim of this paper is to provide an assessment of John R. Commons’ adoption of Wesley N. Hohfeld’s framework of jural opposites and correlatives in order to construct his transactional approach to the study of institutions.
Luca Fiorito
core  

Information commons planning: Strategic and operational considerations [PDF]

open access: yes, 2010
This session will introduce you to planning issues and operational elements that you will need to consider when implementing an Information Commons. The planning process, service models, collaboration issues and relationship building will be discussed ...
Hester, Mountifield
core  

How common is common? [PDF]

open access: yesBMJ, 2004
Do patients with venous ulcers get pain A: most of the time? B: commonly? C: often? D: rarely? We all use imprecise terms in our writing, but such terms cause confusion when they are used in examination questions. We have all experienced sitting an examination and wondering what …
openaire   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Semi-empirical estimates of stratospheric circulation and the lifetimes of chlorofluorocarbons and carbon tetrachloride

open access: yesCommunications Earth & Environment
Chlorofluorocarbons (CFCs) and carbon tetrachloride (CCl4) are ozone-depleting substances with high radiative efficiencies; however, uncertainties in their atmospheric lifetimes hinder top-down emission monitoring efforts.
Stephen Bourguet   +2 more
doaj   +1 more source

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