Results 131 to 140 of about 6,508,204 (342)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Distribution and frequency of wildfire in California riparian ecosystems

open access: yesEnvironmental Research Letters, 2017
Although wildfire has been recognized as having important ecological impacts on California’s riparian environments, understanding of its occurrence is largely anecdotal, based on studies of fire impacts in scattered locations.
Jacob Bendix, Michael G Commons
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Auditing the 2020 ‘Christmas Decree’: communicating pandemic restrictions during Italy’s first ‘Covid-Christmas’

open access: yesItalian Political Science
This article investigates the online public reception of travel restrictions during the Covid-19 pandemic in Italy and the role of civil society in communicating them.
Riccardo Nanni, Maurizio Napolitano
doaj   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Enterprise creation & anti-commons in developing economies: evidence from World Bank doing business data [PDF]

open access: yes
: This paper looks at the tragedy of anti-commons and its implications on enterprise creation in developing economies. The most important features of the anti-commons are captured under a simplified theoretical economic model. The empirical part uses the
Driouchi, Ahmed, Malki, Karim
core   +1 more source

Using Digital Art to make the Tension beetween Capital and Commons Transparent. Innovation in shaping knowledge of Internet business practices as a form of cultural knowledge\ud [PDF]

open access: yes, 2012
This paper examines a digital art performance by Ubermorgen.com called Google Will Eat Itself (GWEI.org) as an example of the tensions between Capital and the public commons.
Kampf, Constance E.
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The challenge of ecological justice in a globalising world [PDF]

open access: yes, 2005
Ecological justice is a challenging concept in relation to the current development of agriculture, including organic agriculture, because it positions social and ecological interests against market liberalism and economic growth.
Alrøe, Hugo F.
core  

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