Results 121 to 130 of about 3,265,734 (307)
The Ag Data Commons presents monthly statistics on engagement and usage in a dashboard. The dashboard uses DKAN Charts and the data in this dataset. Initial product developed by Shivam Saith, Univ.
Ag Data Commons (17478225)
core +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Research Background. The project here presented is an investigation of alternative architectural solutions that combine the need to limit social isolation while providing specialised supportive services for homeless youth in Southport Australia.
Bischeri, Cecilia, Soleckhan, Carina
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The Drama of Fishing Commons: Cournot-Nash Model and Cooperation [PDF]
Cournot-Nash model; drama of the commons; cooperation; game theory; fishing effort.
José António Filipe
core
"Afterword: After the commons -commoning"
Commoning over time generates customs in common and therefore commonalities. The political mobilizations of the past years may well be understood as a form of urban commoning. However, while such mobilizations may sometimes understand themselves as anticapitalist, one should resist the apparently logical idea (1) that the use values off ered by an ...
openaire +3 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Analyzing the anarchist commons in Montreal, Canada using participatory action research interviews with 127 participants, we find that anti-authoritarian groups and networks addressing disparate but connected struggles are building an anarchist commons ...
Breton, Emilie +3 more
core
Scaling up CO2 removal is crucial to achieve net-zero targets and limit global warming. To engage with publics and ensure a social licence to deploy large-scale carbon dioxide removal (CDR), better understanding of public perceptions of these ...
Tim Repke +3 more
doaj +1 more source

