Results 61 to 70 of about 3,265,734 (307)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Case studies (Swinburne Commons)
Swinburne Commons is the centralised service for the management and distribution of digital media at Swinburne University. This video describes three digital media projects at Swinburne that we have been involved with: 1) EndNote tutorials; 2) MathsCasts
Swinburne Commons
core
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
This paper presents in an objective way the changes in geographic–economic and social–geographic structures in Chile. It analyzes the growth of the population and some of its reprecussions: Educational Reform; unemployment: Chilean Agrarian Reform; the ...
Áurea Commons de la Rosa
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
A link to the Creative Commons website, outlining all you need to know about attaching a licence to your open access materials.
Creative Commons
core
mapping-commons/sssom-py: v0.3.20
What's Changed help CLI command by @hrshdhgd in https://github.com/mapping-commons/sssom-py/pull/335 Labels not required while parsing obo-json by @hrshdhgd in https://github.com/mapping-commons/sssom-py/pull/331 Clarifies possible doc format in --help ...
Harshad
core +1 more source
On the use of computer‐assistance to facilitate systematic mapping
The volume of published academic research is growing rapidly and this new era of “big literature” poses new challenges to evidence synthesis, pushing traditional, manual methods of evidence synthesis to their limits.
Neal R. Haddaway +6 more
doaj +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source

