Results 61 to 70 of about 3,265,734 (307)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Case studies (Swinburne Commons)

open access: yes, 2016
Swinburne Commons is the centralised service for the management and distribution of digital media at Swinburne University. This video describes three digital media projects at Swinburne that we have been involved with: 1) EndNote tutorials; 2) MathsCasts
Swinburne Commons
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Análisis comparativo de la población de la cuidad de México según censos de población 1930 - 1950 - 1970

open access: yesInvestigaciones Geográficas, 1971
This paper presents in an objective way the changes in geographic–economic and social–geographic structures in Chile. It analyzes the growth of the population and some of its reprecussions: Educational Reform; unemployment: Chilean Agrarian Reform; the ...
Áurea Commons de la Rosa
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Creative Commons

open access: yes, 2010
A link to the Creative Commons website, outlining all you need to know about attaching a licence to your open access materials.
Creative Commons
core  

mapping-commons/sssom-py: v0.3.20

open access: yes, 2023
What's Changed help CLI command by @hrshdhgd in https://github.com/mapping-commons/sssom-py/pull/335 Labels not required while parsing obo-json by @hrshdhgd in https://github.com/mapping-commons/sssom-py/pull/331 Clarifies possible doc format in --help ...
Harshad
core   +1 more source

On the use of computer‐assistance to facilitate systematic mapping

open access: yesCampbell Systematic Reviews, 2020
The volume of published academic research is growing rapidly and this new era of “big literature” poses new challenges to evidence synthesis, pushing traditional, manual methods of evidence synthesis to their limits.
Neal R. Haddaway   +6 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

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