Results 111 to 120 of about 726,254 (280)

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Direitos humanos, orientação sexual e identidade de gênero na commonwealth: da História e do Direito ao desenvolvimento de diálogos ativistas e internacionais

open access: yesEstudos de Sociologia, 2017
As temáticas de orientação sexual e identidade de gênero estão chegando ao centro dos debates mundiais sobre direitos humanos e mudança social.
Corinne Lennox, Matthew Waites
doaj  

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold   +12 more
wiley   +1 more source

What's up with the temperature in Mugar? #hotncold [PDF]

open access: yes, 2012
Blog entry from the "Uncommon Blog." Q&A with Tom Casserly, Associate University Librarian for Undergraduate & DIstaance Learning, about temperature fluctuations inside Mugar Memorial Library's space at 771 Commonwealth ...
Mugar Greene Scholars
core  

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Accuracy of Diagnostic Codes and Algorithms Used to Identify Rheumatoid Arthritis and Juvenile Idiopathic Arthritis in Administrative Claims and Electronic Health Records: Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective This systematic review aimed to assess the diagnostic accuracy of algorithms used to identify rheumatoid arthritis and juvenile idiopathic arthritis in electronic health records. Methods We searched Medline, Embase, and Cochrane Central Register for Controlled Trials databases and included studies that validated case definitions against a ...
Constanza Saka‐Herrán   +10 more
wiley   +1 more source

Closing the Divide: How Medical Homes Promote Equity in Health Care [PDF]

open access: yes, 2007
Presents findings from the Commonwealth Fund 2006 Health Care Quality Survey, and demonstrates how having stable insurance, a regular provider and, in particular, a medical home, improves health care access and quality among vulnerable ...
Anne C. Beal   +4 more
core  

Testing a Personalized Approach to Chronic Low Back Pain: A Randomized Controlled Trial in Older Veterans

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to test the efficacy of personalized treatment of older veterans with chronic low back pain (CLBP) delivered by Aging Back Clinics (ABCs) as compared with usual care (UC). Methods Two hundred ninety‐nine veterans aged 65 to 89 with CLBP from three Veterans Affairs (VA) medical centers underwent baseline testing, randomization to ABC ...
Debra K. Weiner   +9 more
wiley   +1 more source

The Role of the Coordination Council on the Issues of Sanitary Protection of the Territories of the Member States of the Commonwealth of Independent States from the Importation and Spread of Particularly Dangerous Infectious Diseases in the Formation of a Unified System for Monitoring and Responding to Emergencies of Sanitary-Epidemiological Nature in the CIS

open access: yesПроблемы особо опасных инфекций
Ensuring the sanitary and epidemiological well-being of the population is impossible without the development of international cooperation in the field of preventing and responding to biological emergency situations.
I. G. Karnaukhov   +3 more
doaj   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti   +19 more
wiley   +1 more source

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