Results 21 to 30 of about 14,764,853 (302)

Non-Communicable Disease Prevention : final prospectus report [PDF]

, 2015
This report describes the Non-Communicable Disease Prevention (NCDP) program for the purpose of the External Program Review (prospectus period 2011-2016). It provides an overview of the program strategies and implementation, presents examples of progress
IDRC. Non-Communicable Disease Prevention Program
core   +1 more source

Effect of CD4 count on Mycobacterium tuberculosis infection rates in people living with HIV: a comparative study in prison and community

Scientific Reports
To evaluate the impact of the CD4 count on ESAT6-CFP10 (EC) skin test, QuantiFERON-TB Gold In-tube test (QFT) and tuberculin skin test (TST) in a large prison and communities in Jiangsu Province among people living with HIV (PLHIV).
Peng Lu, Yilin Lian, Zhongqi Li, Kai Wu, Zhuping Xu, Hao Xue, Jincheng Li, Xing Zhang, Rong Wang, Xiaoyan Ding, Jingjing Pan, Hui Ding, Qiao Liu, Limei Zhu, Haitao Yang   +14 more
doaj   +1 more source

Cross-sectional study on prevalence and risk factors for falls among the elderly in communities of Guangdong province, China

BMJ Open, 2022
Objective This study aims to investigate the prevalence and risk factors of falls among the elderly in Guangdong, China.Methods A cross-sectional study was conducted in six communities of Guangdong province.
Chuan Li, Xue-yan Zheng, Xiao-jun Xu, Li-feng Lin, Xia-zi Lin, Rui-lin Meng, Dan-dan Peng, Hao-feng Xu   +7 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Associations of total physical activity with all-cause and cardiovascular disease mortality in Chinese adults: a prospective study

BMC Public Health
Background Evidence regarding the associations of total physical activity with all-cause and cardiovascular disease (CVD) mortality in Chinese adults is limited. The study aimed to evaluate the relationships between them.
Yanan Wan, Jinxin Yu, Hao Yu, Yu Qin, Renqiang Han, Xikang Fan, Xiaoqun Pan, Jie Yang, Quanyong Xiang, Yongqing Zhang, Ran Tao, Jinyi Zhou, Jian Su   +12 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Dengue Situation in Bangladesh: An Epidemiological Shift in terms of Morbidity and Mortality

Canadian Journal of Infectious Diseases and Medical Microbiology, 2019
The escalating dengue situation in Bangladesh has been emerging as a serious public health problem in terms of morbidity and mortality. Results of analysis of 40,476 cases of Bangladesh occurring during 2000–2017 indicated that 49.73% of the dengue cases
Pulak Mutsuddy, Sanya Tahmina Jhora, Abul Khair Mohammad Shamsuzzaman, S. M. Golam Kaisar, Md Nasir Ahmed Khan   +4 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source