Results 41 to 50 of about 14,764,853 (302)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Uniformity in Control of Communicable Diseases

American Journal of Public Health and the Nations Health, 1942
AT the forty-third annual meeting of the American Public Health Association and the fifteenth annual conference of sanitary officers of the State of New York at Rochester, N. Y., a symposium on the administrative control of infectious diseases was held on September 10, 1915, under the joint auspices of the Section of Public Health Officials and the ...
openaire   +3 more sources

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Factors associated with frailty status compared to pre-frailty in community-dwelling older adults: a cross-sectional study

Frontiers in Public Health
ObjectiveTo identify factors distinguishing frail from pre-frail status in community-dwelling older adults and construct a risk prediction model with logistic regression as the primary method to identify independent risk factors, and a neural network as ...
Wei Li, Xiaodan Xue, Dandan Li, Yi Pan, Meiqiu Xie, Ying Zhang, Wenlong Zheng, Mingyue Zhang   +7 more
doaj   +1 more source

Communicable Diseases and Outbreak Control.

Turkish journal of emergency medicine, 2016
Infectious disease during an emergency condition can raise the death rate 60 times in comparison to other causes including trauma. An epidemic, or outbreak, can occur when several aspects of the agent (pathogen), population (hosts), and the environment create an ideal situation for spread.
openaire   +2 more sources

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Clinical characteristics and risk factors of Hepatitis E virus infection in Zhejiang Province: a multicenter case–control study

Frontiers in Public Health
IntroductionHepatitis E (HE), caused by the Hepatitis E virus (HEV), is a significant cause of acute viral hepatitis globally and a major public health concern, particularly in specific high-prevalence areas in China, which have diverse transmission ...
Yijuan Chen, Jian Gao, Wanwan Sun, Weiping Zhu, Pingping Wang, Xiaobin Ren, Yumeng Wu, Jianli Zhang, Ziping Miao   +8 more
doaj   +1 more source

Different responses of weather factors on hand, foot and mouth disease in three different climate areas of Gansu, China

BMC Infectious Diseases, 2018
Background To determine the linear and non-linear interacting relationships between weather factors and hand, foot and mouth disease (HFMD) in children in Gansu, China, and gain further traction as an early warning signal based on weather variability for
Faxiang Gou, Xinfeng Liu, Jian He, Dongpeng Liu, Yao Cheng, Haixia Liu, Xiaoting Yang, Kongfu Wei, Yunhe Zheng, Xiaojuan Jiang, Lei Meng, Wenbiao Hu   +11 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source