Results 61 to 70 of about 2,578,068 (346)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Dengue Situation in Bangladesh: An Epidemiological Shift in terms of Morbidity and Mortality

Canadian Journal of Infectious Diseases and Medical Microbiology, 2019
The escalating dengue situation in Bangladesh has been emerging as a serious public health problem in terms of morbidity and mortality. Results of analysis of 40,476 cases of Bangladesh occurring during 2000–2017 indicated that 49.73% of the dengue cases
Pulak Mutsuddy, Sanya Tahmina Jhora, Abul Khair Mohammad Shamsuzzaman, S. M. Golam Kaisar, Md Nasir Ahmed Khan   +4 more
doaj   +1 more source

The Vaccine Hesitancy Profiles and Determinants of Seasonal Influenza among Chinese Community Healthcare Workers: A Cross-Sectional Study

Vaccines, 2022
This paper is an evaluation of seasonal influenza vaccination hesitancy (IVH) and its determinants among community HCWs in Chongqing, a city in southwest China.
Xianxian Yang, Wenge Tang, Qiang Tan, Deqiang Mao, Xianbin Ding   +4 more
doaj   +1 more source

Direction & Dilemma of Tropical Oral Health: a position paper [PDF]

, 2006
A number of tropical and communicable diseases are evident as oral manifestations. The tropical and communicable disease of oral health concern is an issue because, not only it is restricted to tropical countries, it is also affecting an underserved ...
Choudhury, C.R.
core  

Regional Initiatives in Support of Surveillance in East Africa: The East Africa Integrated Disease Surveillance Network (EAIDSNet) Experience. [PDF]

, 2013
The East African Integrated Disease Surveillance Network (EAIDSNet) was formed in response to a growing frequency of cross-border malaria outbreaks in the 1990s and a growing recognition that fragmented disease interventions, coupled with weak laboratory
Bond KC, Gresham L, James Kariuki, Leonard E.G Mboera, Maurice Ope, Mayala BK, Mboera LEG, Miriam Schneidman, Mwihaki Kimura, Olago D, Ramana N.V Gandham, Shikanga O, Stanley Sonoiya, WHO, WHO   +14 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effect of CD4 count on Mycobacterium tuberculosis infection rates in people living with HIV: a comparative study in prison and community

Scientific Reports
To evaluate the impact of the CD4 count on ESAT6-CFP10 (EC) skin test, QuantiFERON-TB Gold In-tube test (QFT) and tuberculin skin test (TST) in a large prison and communities in Jiangsu Province among people living with HIV (PLHIV).
Peng Lu, Yilin Lian, Zhongqi Li, Kai Wu, Zhuping Xu, Hao Xue, Jincheng Li, Xing Zhang, Rong Wang, Xiaoyan Ding, Jingjing Pan, Hui Ding, Qiao Liu, Limei Zhu, Haitao Yang   +14 more
doaj   +1 more source

Adult non-communicable disease mortality in Africa and Asia: evidence from INDEPTH Health and Demographic Surveillance System sites. [PDF]

, 2014
BACKGROUND: Mortality from non-communicable diseases (NCDs) is a major global issue, as other categories of mortality have diminished and life expectancy has increased.
Adjei, A, Alam, N, Ansah, P, Bagagnan, CH, Bangha, M, Bauni, E, Bhuiya, A, Bonfoh, B, Byass, P, Chuc, NT, Crampin, A, Debpuur, C, Delaunay, V, Diallo, A, Douillot, L, Ezeh, A, Gomez, P, Gyapong, M, Gómez-Olivé, FX, Haile, F, Hanifi, SM, Herbst, K, Jasseh, M, Juvekar, S, Kahn, K, Kant, S, Khan, WA, Kone, S, Kyobutungi, C, Lankoandé, B, Laserson, KF, Lele, P, Melaku, YA, Misra, P, Mochamah, G, Mossong, J, Ndila, C, Ngoran, EK, Nyaguara, A, Nyirenda, M, Odhiambo, FO, Oduro, A, Oti, S, Phillips-Howard, P, Price, A, Rai, SK, Rossier, C, Sankoh, OA, Sarpong, D, Sié, A, Sokhna, C, Soura, AB, Streatfield, PK, Tollman, SM, Utzinger, J, Wak, G, Weldearegawi, B, Williams, TN, Zabré, P   +58 more
core   +5 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Immunization strategies targeting newly arrived migrants in Non-EU countries of the mediterranean basin and black sea [PDF]

, 2017
Background: The World Health Organization recommends that host countries ensure appropriate vaccinations to refugees, asylum seekers and migrants. However, information on vaccination strategies targeting migrants in host countries is limited. Methods: In
Declich, Silvia, Del Manso, Martina, Dente, Maria Grazia, Giambi, Cristina, Mediterranean Basin Black Sea, Montano-Remacha, Carmen, Napoli, Christian, Riccardo, Flavia   +7 more
core   +1 more source