Results 81 to 90 of about 2,578,068 (346)

A rare case of human infection with Orf virus in China, 2024

Frontiers in Cellular and Infection Microbiology
Orf virus is a globally distributed zoonotic pathogen that mainly infects sheep and goats, although cases of human infection have been occasionally reported. In this study, we reported a rare case of human infection with Orf virus in China. A 66-year-old
Miao Lu, Yumin Liang, Haijian Zhou, Hai Jiang, Xueyun Wang, Wenguo Jiang, Xihong Sun, Shuguang Zhong, Kun Li   +8 more
doaj   +1 more source

Direct detection of Corynebacterium striatum, Corynebacterium propinquum, and Corynebacterium simulans in sputum samples by high-resolution melt curve analysis

BMC Infectious Diseases, 2021
Background Pulmonary infections caused by non-diphtheriae corynebacteria are increasing. However, rapid identification of Corynebacterium species poses a challenge due to the low genetic variation within the genus.
Shuai Xu, Xiaotong Qiu, Xuexin Hou, Haijian Zhou, Dongke Chen, Xuebing Wang, Lichao Han, Dan Li, Lina Sun, Xingzhao Ji, Minghui Li, Jingshan Zhang, Mengtong Li, Zhenjun Li   +13 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Modeling the burden of long COVID in California with quality adjusted life-years (QALYS)

Scientific Reports
Individuals infected with SARS-CoV-2 may develop post-acute sequelae of COVID-19 (“long COVID”) even after asymptomatic or mild acute illness. Including time varying COVID symptom severity can provide more informative burden estimates for public health ...
Sophie Zhu, Kalyani McCullough, Jake M. Pry, Seema Jain, Lauren A. White, Tomás M. León   +5 more
doaj   +1 more source

Factors associated with frailty status compared to pre-frailty in community-dwelling older adults: a cross-sectional study

Frontiers in Public Health
ObjectiveTo identify factors distinguishing frail from pre-frail status in community-dwelling older adults and construct a risk prediction model with logistic regression as the primary method to identify independent risk factors, and a neural network as ...
Wei Li, Xiaodan Xue, Dandan Li, Yi Pan, Meiqiu Xie, Ying Zhang, Wenlong Zheng, Mingyue Zhang   +7 more
doaj   +1 more source

Different responses of weather factors on hand, foot and mouth disease in three different climate areas of Gansu, China

BMC Infectious Diseases, 2018
Background To determine the linear and non-linear interacting relationships between weather factors and hand, foot and mouth disease (HFMD) in children in Gansu, China, and gain further traction as an early warning signal based on weather variability for
Faxiang Gou, Xinfeng Liu, Jian He, Dongpeng Liu, Yao Cheng, Haixia Liu, Xiaoting Yang, Kongfu Wei, Yunhe Zheng, Xiaojuan Jiang, Lei Meng, Wenbiao Hu   +11 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Spicy food consumption is associated with abdominal obesity among Chinese Han population aged 30–79 years in the Sichuan Basin: a population-based cross-sectional study

BMC Public Health, 2022
Background Few animal experiments and volunteer-based intervention studies have showed a controversial effect of spicy foods on abdominal obesity. We aimed to examine the association between spicy food frequency, spicy flavor, and abdominal obesity among
Xianxian Yang, Wenge Tang, Deqiang Mao, Xiang Liu, Wen Qian, Yingxue Dai, Liling Chen, Xianbin Ding   +7 more
doaj   +1 more source

Communicable diseases: provisional summary 2003. [PDF]

, 2004
This report summarises the main trends in communicable disease in Northern Ireland during 2003. It is primarily based on laboratory reports forward to CDSC (NI) and information supplied by Consultants in Communicable Disease Control.

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