Results 91 to 100 of about 2,470,242 (348)

Communicable Disease Center activities, 1949-1950. [PDF]

On cover: Epidemic aid, Operations, Training, Laboratory services, Investigations.The Communicable Disease Center, organizationally a Division of the Bureau of State Services \ub7 of the Public Health Service, primarily is concerned with assisting State ...

core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Have purpose‐built vaccine refrigerators reduced the cost of vaccine losses in South Australia?

Australian and New Zealand Journal of Public Health, 2012
Objectives: There is limited epidemiological data on the performance of different refrigerator types for vaccine storage in the real world. This study aims to measure if the introduction of purpose‐built vaccine refrigerators has reduced the cost of ...
Katina D'Onise, Sara Almond, Breda MacDonald, Maureen Watson, Sophie Scrimgeour   +4 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

A process evaluation of Ontario, Canada’s 2023–24 older-adult RSV vaccination program

Human Vaccines & Immunotherapeutics
Respiratory syncytial virus (RSV) is a major cause of respiratory illness in older adults. During the 2023–2024 respiratory season, Ontario was the first and only province in Canada to launch a publicly funded RSV vaccination program for older adults.
Reed Morrison, Janice Sarmiento, Jamie Park, Gillian Lim, Christina Renda, Michael Whelan, Allison McGeer, Tara Harris, Sarah E. Wilson   +8 more
doaj   +1 more source

Activities Report: Vector Control and Investigations Branch. [PDF]

The Vector Control and Investigations Branch was officially organized on October 5, 1951, by order of the Medical Director in Charge. The components of the new Branch were formerly the Engineering and Entomology Branches and the plague studies and ...

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Effect of Novartis Access on availability and price of non-communicable disease medicines in Kenya: a cluster-randomised controlled trial.

Lancet Global Health, 2019
BACKGROUND Novartis Access is a Novartis programme that offers a portfolio of non-communicable disease medicines at a wholesale price of US$1 per treatment per month in low-income and middle-income countries. We evaluated the effect of Novartis Access in
P. Rockers, R. Laing, P. Ashigbie, M. Onyango, Carol Mukiira, V. Wirtz   +5 more
semanticscholar   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Characterization of Escherichia coli strains producing Shiga Toxin 2f subtype from domestic Pigeon

Scientific Reports
Shiga toxin-producing Escherichia coli (STEC) can cause mild diarrhea even severe hemolytic uremic syndrome (HUS). Shiga toxin (Stx) is the primary virulence factor. Two Stx types and several subtypes have been identified.
Xi Yang, Yun Ma, Fujian Chu, Hua Wang, Xinxia Sui, Qian Liu, Peihua Zhang, Xiangning Bai, Biao Duan, Yanwen Xiong   +9 more
doaj   +1 more source

First Africa non-communicable disease research conference 2017: sharing evidence and identifying research priorities

Journal of Global Health, 2019
Non-communicable diseases (NCDs) prevalence is rising fastest in lower income settings, and with more devastating outcomes compared to High Income Countries (HICs).
Kenneth Juma, Pamela A. Juma, S. Mohamed, J. Owuor, Agnes N Wanyoike, David Mulabi, George Odinya, Maureen Njeru, G. Yonga   +8 more
semanticscholar   +1 more source