Results 71 to 80 of about 14,764,853 (302)

Communicable Disease Center activities, 1949-1950. [PDF]

On cover: Epidemic aid, Operations, Training, Laboratory services, Investigations.The Communicable Disease Center, organizationally a Division of the Bureau of State Services \ub7 of the Public Health Service, primarily is concerned with assisting State ...

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Characteristics and timeliness of intervention in 47 school-based enterovirus outbreaks in Zhejiang Province, China

Frontiers in Public Health
BackgroundHand, foot, and mouth disease (HFMD) and herpangina (HA) are common infectious diseases in children that can frequently lead to outbreaks. Analyzing the characteristics of school-based outbreaks and evaluating the timeliness of prevention and ...
Yijuan Chen, Wanwan Sun, Xiaobin Ren, Xiaomin Gu, Kai Song, Pingping Wang, Yanli Cao, Jianmin Jiang, Jianmin Jiang, Ziping Miao, Ziping Miao   +10 more
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Cancer survival trends in Shandong Province, China (2016–2024): a population-based study

Scientific Reports
This study provides a comprehensive overview of long-term cancer survival in Shandong Province, China. We aimed to estimate the most recent survival rates among newly diagnosed cancer patients in Shandong during 2022–2024 and analyze temporal trends in ...
Fan Jiang, Junli Tang, Zilong Lu, Bingyin Zhang, Jie Chu, Aiqiang Xu, Zhentao Fu, Xiaolei Guo   +7 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Population aging and changes in mortality from four major noncommunicable diseases in Suzhou, China: a population-based study from 2000 to 2020

BMC Public Health
Background Population aging is accelerating worldwide and poses long-term health challenges for four major chronic noncommunicable diseases (NCDs), including cancer, cardiovascular disease (CVD), chronic respiratory disease (CRD), and diabetes.
Chunyan Huang, Menglin Bai, Yujie Hua, Huanhuan Zhao, Junpeng Cui, Zibo Gao, Lamei Shen, Qing Zhang, Hao Wu, Haitao Wang, Yan Lu   +10 more
doaj   +1 more source

Associations of changes in waist circumference and BMI with variation of fasting blood glucose among middle aged and elderly residents at high cardiovascular risk: a follow-up study in Jiangsu province

Zhongguo gonggong weisheng
Objective To investigate associations of changes in waist circumference (WC) and body mass index (BMI) with the variation of fasting blood glucose among middle aged and elderly residents with high cardiovascular risk.
Xun WU, Yu QIN, Jian SU, Lulu CHEN, Lan CUI, Ran TAO, Jinyi ZHOU   +6 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Activities Report: Vector Control and Investigations Branch. [PDF]

The Vector Control and Investigations Branch was officially organized on October 5, 1951, by order of the Medical Director in Charge. The components of the new Branch were formerly the Engineering and Entomology Branches and the plague studies and ...

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