Results 131 to 140 of about 198,227 (313)

Maribel Gamon - Multidrug-Resistant Tuberculosis in India: Solving a Problem by Reconstructing the Public Health Infrastructure [PDF]

open access: yes, 2013
Mycobacterium tuberculosis, commonly referred to as TB, is responsible for causing about 630,000 cases per year of infectious diseases worldwide. Recently, multidrug resistant tuberculosis (MDR-TB) has become an alarming public health concern.
Gamon, Maribel
core   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

open access: yesAdvanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo   +7 more
wiley   +1 more source

Emerging role of exosomes as a liquid biopsy tool for diagnosis, prognosis & monitoring treatment response of communicable & non-communicable diseases

open access: yesIndian Journal of Medical Research
Abstract From an initial thought of being used as a cellular garbage bin to a promising target for liquid biopsies, the role of exosomes has drastically evolved in just a few years of their discovery in 1983. Exosomes are naturally secreted nano-sized vesicles, abundant in all types of body fluids and can be isolated intact even from the ...
Yadav, Rajbala   +3 more
openaire   +2 more sources

LL‐37 Driven Phase Transition and Stacking in Oligolamellar Gram‐Negative Bacterial Membrane Models

open access: yesAdvanced Functional Materials, EarlyView.
This work establishes oligolamellar bacterial membrane models to investigate how LL‐37 disrupts the complex dual‐bilayer architecture of Gram‐negative bacteria. Combining SAXS, cryo‐TEM, electrophoretic mobility measurements, and coarse‐grained simulations, it reveals cardiolipin‐driven phase transitions leading to bicelle‐like structures and membrane ...
Bettina Tran   +5 more
wiley   +1 more source

Seroprevalence and Associated Risk Factors of Human Brucellosis in a Farming and Animal Health Community in South Africa, 2015–2016

open access: yesTropical Medicine and Infectious Disease
Brucellosis is a widespread zoonotic disease and a major contributor to febrile illness, often underdiagnosed. This study investigated the seroprevalence of brucellosis and the associated exposure factors within South African farming and animal health ...
Jennifer Rossouw   +5 more
doaj   +1 more source

Biological Terrorism, Emerging Diseases, and National Security [PDF]

open access: yes, 1998
Examines the extent to which bioterrorist attacks have proven or may prove difficult to distinguish from outbreaks of emerging diseases. Makes recommendations for how the U.S.
Christopher F. Chyba
core  

Burden of Non-Communicable Diseases and Emerging Attention in Gandaki Province, Nepal

open access: yesJournal of Nepal Medical Association
Non-communicable diseases have become a major health challenge globally, including in Nepal. Deaths due to non-communicable diseases in Nepal are increasing, accounting more than half of total deaths. Major contributors to deaths due to non-communicable diseases include cardiovascular diseases, chronic respiratory diseases, cancers, digestive diseases ...
Khim Bahadur Khadka, Deepak Paudel
openaire   +2 more sources

Establishing a Model Precursor System: Over a Decade of Research on Carbon Dots from the Citric Acid‐Urea System

open access: yesAdvanced Functional Materials, EarlyView.
The citric acid/urea (CA‐Urea) precursor system offers a versatile, scalable route to carbon dots with tunable luminescence and multifunctionality. Mechanistic insights into precursor chemistry and reaction parameters have enabled doping, surface modification, and hybridization strategies, yielding CDs for luminescent devices, sensing, catalysis ...
Yupeng Liu   +10 more
wiley   +1 more source

Global Public Goods and Global Health [PDF]

open access: yes, 2012
The repair rate on electron beam welded diaphragm hasn’t been at the desired level at Siemens SIT for several years. An improvement program the past five years has reduce the repair rate from 60% to 12-15% but the goal of 5% repair rate hasn’t been met ...
Gartner, David
core   +1 more source

Multi‐Scale Interface Engineering of MXenes for Multifunctional Sensory Systems

open access: yesAdvanced Functional Materials, EarlyView.
MXenes, as two‐dimensional transition metal carbides and nitrides, demonstrate remarkable capabilities for multifunctional sensing applications. This review systematically examines multi‐scale interface engineering approaches that enhance sensing performance, enable diverse detection functionalities, and improve system‐level compatibility in MXene ...
Jiaying Liao, Sin‐Yi Pang, Jianhua Hao
wiley   +1 more source

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