Results 131 to 140 of about 9,252,342 (407)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Tobacco use and its determinants in the 2015 Kenya WHO STEPS survey

open access: yesBMC Public Health, 2018
Background According to the World Health Organization (WHO), in 2015, over 1.1 billion people smoked tobacco, which represents around 15% of the global population. In Africa, around one in five adults smoke tobacco.
Christine Ngaruiya   +6 more
doaj   +1 more source

An ICT-Based Real-Time Surveillance System for Controlling Dengue in Sri Lanka [PDF]

open access: yesarXiv, 2014
Dengue is a notifiable communicable disease in Sri Lanka since 1996. Dengue fever spread rapidly among people living in most of the districts of Sri Lanka. The present notification system of dengue communicable diseases which is enforced by law is a passive surveillance system carried out by the public health care professionals.
arxiv  

Time Evolution of Disease Spread on Networks with Degree Heterogeneity [PDF]

open access: yes, 2007
Two crucial elements facilitate the understanding and control of communicable disease spread within a social setting. These components are, the underlying contact structure among individuals that determines the pattern of disease transmission; and the evolution of this pattern over time.
arxiv   +1 more source

Quantifying the spread of communicable diseases with immigration of infectious individuals [PDF]

open access: yesarXiv, 2023
We construct a set of new epidemiological thresholds to address the general problem of spreading and containment of a disease with influx of infected individuals when the classic $\mathcal R_0$ is no longer meaningful. We provide analytical properties of these indices and illustrate their usefulness in a compartmental model of COVID-19 with data taken ...
arxiv  

Environmental Endocrine-Disrupting Chemical Exposure: Role in Non-Communicable Diseases

open access: yesFrontiers in Public Health, 2020
The exponential growth of pollutant discharges into the environment due to increasing industrial and agricultural activities is a rising threat for human health and a biggest concern for environmental health globally.
Manoj Kumar   +6 more
semanticscholar   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

State model for partly undetected non-communicable diseases (NCDs) [PDF]

open access: yesarXiv, 2014
This article proposes an age-structured compartment model for irreversible diseases with a pre-clinical state of undiagnosed cases that precedes the diagnosis. The model is able to cope with mortality rates differing between the pre-clinical and the clinical state (differential mortality).
arxiv  

Gut Microbiota during Dietary Restrictions: New Insights in Non-Communicable Diseases

open access: yesMicroorganisms, 2020
In recent decades, there has been a growing interest in dietary restrictions for their promising effects on longevity and health span. Indeed, these strategies are supposed to delay the onset and burden of non-communicable diseases (NCDs) such as obesity,
E. Rinninella   +8 more
semanticscholar   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

open access: yesFEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu   +6 more
wiley   +1 more source

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