Results 51 to 60 of about 714,630 (331)

Microbiological and clinical characteristics of invasive Group B Streptococcal blood stream infections in children and adults from Qatar

open access: yesBMC Infectious Diseases, 2022
Introduction Group B Streptococci (GBS) colonize almost one third of human gastrointestinal and genitourinary tracts, particularly in females. The aim of this study is to evaluate the epidemiology, microbiological characteristics, and clinical outcomes ...
Maisa Ali   +8 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Investigation of Salmonella Enteritidis outbreaks in South Africa using multi-locus variable-number tandem-repeats analysis, 2013-2015

open access: yesBMC Infectious Diseases, 2017
Background Salmonella enterica serovar Enteritidis (Salmonella Enteritidis) has become a significant pathogen in South Africa, and the need for improved molecular surveillance of this pathogen has become important.
Munyadziwa Muvhali   +3 more
doaj   +1 more source

The first consecutive 5000 patients with Coronavirus Disease 2019 from Qatar; a nation-wide cohort study

open access: yesBMC Infectious Diseases, 2020
Background There are limited data on Coronavirus Disease 2019 (COVID-19) outcomes at a national level, and none after 60 days of follow up. The aim of this study was to describe national, 60-day all-cause mortality associated with COVID-19, and to ...
Ali S. Omrani   +29 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Research needs for an improved primary care response to chronic non-communicable diseases in Africa. [PDF]

open access: yes, 2010
With non-communicable diseases (NCDs) projected to become leading causes of morbidity and mortality in developing countries, research is needed to improve the primary care response, especially in sub-Saharan Africa.
Abegunde   +29 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Are Communicable Diseases Only Communicable?

open access: yes, 2021
For half a century, the so-called epidemiological transition model has guided the interpretation of mortality data. Based on long-term trends in morbidity, it focuses on declining mortality from communicable diseases and the rise of non-communicable chronic diseases (primarily cancer and cardiovascular diseases).
Cavalin, Catherine   +1 more
openaire   +1 more source

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