Results 61 to 70 of about 2,144,942 (261)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Candida glabrata chorioamnionitis following IVF pregnancy

IDCases
Fungal chorioamnionitis is a rare but potentially life-threatening complication of pregnancy with significant maternal and fetal consequences. We describe a severe case of Candida glabrata chorioamnionitis in a 19-week twin pregnancy conceived through in
Junais Koleri, Hani Ghassan Hamad, Fatma Ben Abid, Sreethish Sasi, Ajithkumar V. Ittaman, Muna AlMaslamani   +5 more
doaj   +1 more source

The first consecutive 5000 patients with Coronavirus Disease 2019 from Qatar; a nation-wide cohort study

BMC Infectious Diseases, 2020
Background There are limited data on Coronavirus Disease 2019 (COVID-19) outcomes at a national level, and none after 60 days of follow up. The aim of this study was to describe national, 60-day all-cause mortality associated with COVID-19, and to ...
Ali S. Omrani, Muna A. Almaslamani, Joanne Daghfal, Rand A. Alattar, Mohamed Elgara, Shahd H. Shaar, Tawheeda B. H. Ibrahim, Ahmed Zaqout, Dana Bakdach, Abdelrauof M. Akkari, Anas Baiou, Bassem Alhariri, Reem Elajez, Ahmed A. M. Husain, Mohamed N. Badawi, Fatma Ben Abid, Sulieman H. Abu Jarir, Shiema Abdalla, Anvar Kaleeckal, Kris Choda, Venkateswara R. Chinta, Mohamed A. Sherbash, Khalil Al-Ismail, Mohammed Abukhattab, Ali Ait Hssain, Peter V. Coyle, Roberto Bertollini, Michael P. Frenneaux, Abdullatif Alkhal, Hanan M. Al-Kuwari   +29 more
doaj   +1 more source

Obesity is a communicable disease

Journal of the Pakistan Medical Association
Obesity has multiple causes and correlates. Usually studied as a metabolic and endocrine disease, with mechanical and musculoskeletal comorbidities, obesity also has a communicable angle to it. Obesity can be considered a communicable disease from the conventional point of view, as it is associated with viral etiology in animal and human models.
Sanjay, Kalra, Madhur, Verma, Nitin, Kapoor   +2 more
openaire   +2 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

A rare case of concurrent longitudinally extensive myelitis and retinal vein occlusion

IDCases
Neurosyphilis can affect multiple organ systems, but simultaneous involvement of the spinal cord and retinal vasculature is exceedingly rare. We report a 36-year-old man presenting first with unilateral branch retinal vein occlusion (BRVO) and, two weeks
Junais Koleri, Musaed Saad A. Al Samawi, Hasan Syed Ahmedullah, Sreethish Sasi, Ajithkumar V. Ittaman, Muna Al Maslamani   +5 more
doaj   +1 more source

Communicable Diseases [PDF]

, 2000
Sanitation, food control, vaccines, and antibiotics have reduced the toll of communicable diseases, saving millions of lives. Smallpox was eradicated in 1977, and poliomyelitis eradication is close. Measles mortality has reduced drastically yet outbreaks occur where immunization lags.
Tulchinsky, Theodore H., Varavikova, Elena A.   +1 more
openaire   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source