Results 51 to 60 of about 3,097,640 (309)

Diethylene glycol poisoning in Gurgaon, India, 1998

Bulletin of the World Health Organization
OBJECTIVE: To discover the cause of acute renal failure in 36 children aged 2 months to 6 years who were admitted to two hospitals in Delhi between 1 April and 9 June 1998.
Jagvir Singh, A.K. Dutta, Shashi Khare, N.K. Dubey, A.K. Harit, N.K. Jain, T.C. Wadhwa, S.R. Gupta, A.C. Dhariwal, D.C. Jain, Rajesh Bhatia, Jotna Sokhey   +11 more
doaj   +1 more source

Clinical characteristics of 10 children with a pediatric inflammatory multisystem syndrome associated with COVID-19 in Iran

BMC Pediatrics, 2020
Background Although symptoms and signs of COVID-19 (Coronavirus disease 2019) in children are milder than adults, there are reports of more severe cases which were defined as pediatric inflammatory multisystem syndrome (PIMS).
Leila Shahbaznejad, Mohammad Reza Navaeifar, Ali Abbaskhanian, Fatemeh Hosseinzadeh, Golnar Rahimzadeh, Mohammad Sadegh Rezai   +5 more
doaj   +1 more source

Non-Communicable Diseases and their Impact on Sustainable Development [PDF]

, 2021
Non-communicable diseases and their impact on sustainable development. -- The situation of non-communicable diseases in the Caribbean. -- Non-communicable diseases: a bane to Caribbean productivity and development.

core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

International law and communicable diseases

Bulletin of the World Health Organization, 2002
Historically, international law has played a key role in global communicable disease surveillance. Throughout the nineteenth century, international law played a dominant role in harmonizing the inconsistent national quarantine regulations of European ...
Aginam Obijiofor
doaj  

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

Whole-genome sequencing for surveillance of Salmonella at a public health institution in South Africa

African Journal of Laboratory Medicine
Background: Whole-genome sequencing (WGS) is transforming communicable disease surveillance globally. The National Institute for Communicable Diseases, South Africa, participates in national laboratory-based surveillance for human isolates of Salmonella.
Anthony M. Smith, Phuti Sekwadi, Hlengiwe M. Ngomane, Bolele Disenyeng, Linda K. Erasmus, Juno Thomas, Dineo Bogoshi, Shannon L. Smouse, Nomsa P. Tau   +8 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Detection of Campylobacter species in stool specimens from patients with symptoms of acute flaccid paralysis in South Africa

Journal of Infection in Developing Countries, 2018
Introduction: Guillain-Barré Syndrome (GBS) is an autoimmune disease characterized by acute or subacute symmetrical ascending motor weakness, areflexia, and mild-to-moderate sensory abnormalities.
Mandile Samantha Thobela, Anthony Marius Smith, Shelina Moonsamy, Heleen du Plessis, Nevashan Govender, Karen Helena Keddy   +5 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source