Results 61 to 70 of about 6,710,857 (253)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Training in communication for family planning : retrospect and prospects [PDF]

open access: yes, 1977
"This project was supported by the Office of Population, U.S. Agency for International Development, AID/csd-1059."For more about the East-West Center, see http://www.eastwestcenter.org/This paper reviews the aims and purposes of communication training ...
Amritmahal, G. R.   +1 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Relationship between dominant hand and ear preference for listening among medical students

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth, 2018
Objective: The aim of the study was to determine dominant hand for routine activities and ear preference for listening among medical students. Mobile phone usage was also studied.
Sandeep Sachdeva, Nidhi Dwivedi
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

The effect of using communication boards on ease of communication and anxiety in mechanically ventilated conscious patients admitted to intensive care units

open access: yesIranian Journal of Nursing and Midwifery Research, 2018
Background: Using mechanical ventilation devices has unique advantages for the patient; however, it can also cause various problems. This study aimed to determine the effect of using communication boards on the ease of communication and anxiety in ...
Seyede-Roghayeh Hosseini   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

New perspectives in international communication [PDF]

open access: yes, 1977
For more about the East-West Center, see http://www.eastwestcenter.org/This volume focuses on three issues: (1) the presumed negative impact on receiving societies of a significant volume of communication of diverse content from sources outside that ...
East-West Communication Institute
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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